Late-onset Leber's hereditary optic neuropathy

E T Ajax; R Kardon

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Late-onset Leber's hereditary optic neuropathy

Journal article

Peer reviewed

Late-onset Leber's hereditary optic neuropathy

E T Ajax and R Kardon

Journal of neuro-ophthalmology, Vol.18(1), pp.30-31

03/1998

PMID: 9532536

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Abstract

Progressive, sequential visual loss in the left and then right eye was reported in a 73-year-old male over three months. The presence of a family history of visual loss and the lack of other findings in association with bilateral cecocentral scotomata led to a diagnosis of new onset Leber's hereditary optic neuropathy, confirmed by the presence of a mutation at the 11,778 position. This case illustrates that Leber's hereditary optic neuropathy may manifest late in life.

Point Mutation

Vision Disorders - diagnosis

Optic Atrophies, Hereditary - genetics

Vision Disorders - genetics

DNA Mutational Analysis

Visual Fields

Humans

Male

Aged

Optic Atrophies, Hereditary - diagnosis

Visual Acuity

Details

Title: Subtitle: Late-onset Leber's hereditary optic neuropathy
Creators: E T Ajax - Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
R Kardon
Resource Type: Journal article
Publication Details: Journal of neuro-ophthalmology, Vol.18(1), pp.30-31
PMID: 9532536
NLM abbreviation: J Neuroophthalmol
ISSN: 1070-8022
eISSN: 1536-5166
Publisher: United States
Language: English
Date published: 03/1998
Academic Unit: Iowa Neuroscience Institute; Ophthalmology and Visual Sciences
Record Identifier: 9983980024902771

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22 Times Cited - Web of Science