Left ventricular diastolic size in patients with normal ejection fraction and elevated left filling pressures

Elias B Hanna; David Luke Glancy; Frederick Helmcke

doi:10.1111/j.1540-8175.2009.01052.x

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$Left ventricular diastolic size in patients with normal ejection fraction and elevated left filling pressures$

Journal article

Peer reviewed

Left ventricular diastolic size in patients with normal ejection fraction and elevated left filling pressures

Elias B Hanna, David Luke Glancy and Frederick Helmcke

Echocardiography (Mount Kisco, N.Y.), Vol.27(5), pp.501-504

05/2010

DOI: 10.1111/j.1540-8175.2009.01052.x

PMID: 20345449

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Abstract

To evaluate the left-ventricular diastolic chamber size in patients with a normal ejection fraction and elevated left-sided filling pressures. The consensus view that patients with normal left ventricular ejection fraction (LVEF) and elevated left-sided filling pressures have a normal left ventricular diastolic size is a point of controversy. We reviewed the coded database of echocardiographic studies performed at one institution between July 2007 and July 2008. We performed a retrospective descriptive study of 35 patients with normal ejection fraction (> or = 55%) and elevated left-sided filling pressures. We looked at their left ventricular internal diastolic diameter (LVIDD). Our population had a high prevalence of hypertension (100%), obesity (63%), diabetes (40%), chronic kidney disease (51%), coronary artery disease (25%), anemia (43%), and left ventricular hypertrophy (65%). Clinical diagnosis of heart failure was documented in 63% of the patients. LVIDD was mildly increased in comparison to a normal historical population: 4.85 + or - 0.5 cm for females, 5.3 + or - 0.5 cm for males, as compared to 4.6 + or - 0.3 cm for normal females (P = 0.045) and 5 + or - 0.4 cm for normal males (P < 0.001). However, the distribution of the indexed LVIDDs in these patients was comparable to the normal population (2.6 + or - 0.4 cm/m(2) for the study population, as compared to 2.7 + or - 0.2 cm/m(2) for the normal population, P = 0.16). In a population of patients with a normal LVEF and high left ventricular filling pressures, the indexed LV diastolic size is not increased in comparison to a normal population. (Echocardiography 2010;27:501-504).

Blood Pressure

Comorbidity

Diastole

Echocardiography, Doppler

Female

Heart Failure - diagnostic imaging

Heart Failure - physiopathology

Humans

Male

Middle Aged

Retrospective Studies

Stroke Volume

Ventricular Dysfunction, Left - diagnostic imaging

Ventricular Dysfunction, Left - physiopathology

Details

Title: Subtitle: Left ventricular diastolic size in patients with normal ejection fraction and elevated left filling pressures
Creators: Elias B Hanna - Louisiana State University
David Luke Glancy - Louisiana State University
Frederick Helmcke - Louisiana State University
Resource Type: Journal article
Publication Details: Echocardiography (Mount Kisco, N.Y.), Vol.27(5), pp.501-504
DOI: 10.1111/j.1540-8175.2009.01052.x
PMID: 20345449
ISSN: 0742-2822
eISSN: 1540-8175
Language: English
Date published: 05/2010
Academic Unit: Cardiovascular Medicine; Internal Medicine
Record Identifier: 9984359904802771

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