Journal article
Lemierre's syndrome due to Fusobacterium necrophorum
The Lancet infectious diseases, Vol.12(10), pp.808-815
10/2012
DOI: 10.1016/S1473-3099(12)70089-0
PMID: 22633566
Abstract
We present a case of a patient with Lemierre's syndrome caused by Fusobacterium necrophorum who developed a right frontal lobe brain abscess. We summarise the epidemiology, microbiology, pathogenesis, clinical presentation, diagnosis, complications, therapy, and outcomes of Lemierre's syndrome. F necrophorum is most commonly associated with Lemierre's syndrome: a septic thrombophlebitis of the internal jugular vein. Patients usually present with an exudative tonsillitis, sore throat, dysphagia, and unilateral neck pain. Diagnosis of septic thrombophlebitis is best confirmed by obtaining a CT scan of the neck with contrast. Complications of the disease include bacteraemia with septic abscesses to the lungs, joints, liver, peritoneum, kidneys, and brain. Treatment should include a prolonged course of intravenous beta-lactam antibiotic plus metronidazole.
Details
- Title: Subtitle
- Lemierre's syndrome due to Fusobacterium necrophorum
- Creators
- Krutika Kuppalli - Department of Medicine, Division of Infectious Diseases, Division of Global Public Health, University of California, San Diego, San Diego, CA 92103-8208, USA. kkuppalli@ucsd.eduDaniel LivorsiNaasha J TalatiMelissa Osborn
- Resource Type
- Journal article
- Publication Details
- The Lancet infectious diseases, Vol.12(10), pp.808-815
- DOI
- 10.1016/S1473-3099(12)70089-0
- PMID
- 22633566
- ISSN
- 1473-3099
- eISSN
- 1474-4457
- Grant note
- T32 DA 023356 / NIDA NIH HHS
- Language
- English
- Date published
- 10/2012
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9984094511902771
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