Journal article
Lesions of endodontic origin and risk of coronary heart disease
Journal of Dental Research, Vol.85(11), pp.996-1000
2006
DOI: 10.1177/154405910608501104
PMID: 17062738
Abstract
A paucity of epidemiologic research exists regarding systemic health consequences of endodontic disease. This study evaluated whether incident radiographically evident lesions of endodontic origin were related to development of coronary heart disease (CHD) among 708 male participants in the VA Dental Longitudinal Study. At baseline and every three years for up to 32 years, participants (who were not VA patients) received complete medical and dental examinations, including full-mouth radiographs. Cox regression models estimated the relationship between incident lesions of endodontic origin and time to CHD diagnosis. Among those < or = 40 years old, incident lesions of endodontic origin were significantly associated with time to CHD diagnosis (p < 0.05), after adjustment for covariates of interest, with hazard ratios decreasing as age increased. Among those > 40 years old, no statistically significant association was observed. These findings are consistent with research that suggests relationships between chronic periodontal inflammation and the development of CHD, especially among younger men.
Details
- Title: Subtitle
- Lesions of endodontic origin and risk of coronary heart disease
- Creators
- D. J CaplanJ. D BeckS OffenbacherJ CaiS KangJ. B ChasenE A KrallR. I Garcia
- Resource Type
- Journal article
- Publication Details
- Journal of Dental Research, Vol.85(11), pp.996-1000
- DOI
- 10.1177/154405910608501104
- PMID
- 17062738
- NLM abbreviation
- J Dent Res
- ISSN
- 0022-0345
- eISSN
- 1544-0591
- Language
- English
- Date published
- 2006
- Academic Unit
- Preventive and Community Dentistry
- Record Identifier
- 9983917678202771
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