Lessons from Leptin's molecular biology: Potential therapeutic actions of recombinant leptin and leptin-related compounds

M L G Correia; W G Haynes

doi:10.2174/138955707779317858

Back

Lessons from Leptin's molecular biology: Potential therapeutic actions of recombinant leptin and leptin-related compounds

Journal article

Peer reviewed

Lessons from Leptin's molecular biology: Potential therapeutic actions of recombinant leptin and leptin-related compounds

M L G Correia and W G Haynes

Mini reviews in medicinal chemistry, Vol.7(1), pp.31-38

01/2007

DOI: 10.2174/138955707779317858

PMID: 17266635

View Online

Abstract

Leptin, a peptide secreted by the white adipose tissue, circulates to the central nervous system and signals the status of body energy stores, regulating feeding behavior and energy balance. As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment.

Leptin - physiology

Recombinant Proteins - metabolism

Recombinant Proteins - therapeutic use

Obesity - drug therapy

Signal Transduction

Humans

Leptin - therapeutic use

Lipid Metabolism

Obesity - physiopathology

Leptin - genetics

Recombinant Proteins - genetics

Details

Title: Subtitle: Lessons from Leptin's molecular biology: Potential therapeutic actions of recombinant leptin and leptin-related compounds
Creators: M L G Correia - General Clinical Research Center, Department of Internal Medicine-157 MRF, University of Iowa, Iowa City, IA, 52242, USA. marcelo-correia@uiowa.edu
W G Haynes
Resource Type: Journal article
Publication Details: Mini reviews in medicinal chemistry, Vol.7(1), pp.31-38
DOI: 10.2174/138955707779317858
PMID: 17266635
ISSN: 1389-5575
eISSN: 1875-5607
Language: English
Date published: 01/2007
Academic Unit: Endocrinology and Metabolism; Internal Medicine
Record Identifier: 9984094661902771

Metrics

9 Record Views

6 Times Cited - Web of Science