Levels of endotoxin in 390 Swedish homes: determinants and the risk for respiratory symptoms in children

Syed Moniruzzaman; Linda Hägerhed Engman; Peter James; Torben Sigsgaard; Peter S Thorne; Jan Sundell; Carl-Gustaf Bornehag

doi:10.1080/09603123.2011.588322

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Levels of endotoxin in 390 Swedish homes: determinants and the risk for respiratory symptoms in children

Journal article

Peer reviewed

Levels of endotoxin in 390 Swedish homes: determinants and the risk for respiratory symptoms in children

Syed Moniruzzaman, Linda Hägerhed Engman, Peter James, Torben Sigsgaard, Peter S Thorne, Jan Sundell and Carl-Gustaf Bornehag

International journal of environmental health research, Vol.22(1), pp.22-36

2012

DOI: 10.1080/09603123.2011.588322

PMID: 21707246

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Abstract

Endotoxins are microbiological agents which ubiquitously exist in an indoor environment, and are believed to be causal agents for a number of diseases. This study investigated the indoor levels and determinants of endotoxins and their impact on asthma and allergy diseases among Swedish pre-school children. House dust samples from 390 homes of 198 case children with asthma and allergy and 202 healthy control children were collected in the Dampness Building and Health (DBH) study. House dust endotoxin levels in the child's bedroom and living rooms ranged from 479-188,000 EU/g dust and from 138-942,000 EU/g dust, respectively. Pet-keeping and agricultural activities were significantly associated with the higher endotoxin concentration levels in indoor dust. Endotoxins in theindoor environment did not associate to asthma and allergy diseases in the children. However, we found an association between endotoxins and the presence of disease symptoms in the sub-group of families without indoor pets.

Dust - analysis

Air Pollutants - analysis

Environmental Monitoring

Humans

Risk Factors

Child, Preschool

Hypersensitivity - immunology

Pets - physiology

Environmental Exposure

Housing

Case-Control Studies

Sweden

Immunoglobulin E - analysis

Asthma - immunology

Air Pollution, Indoor

Child

Endotoxins - analysis

Details

Title: Subtitle: Levels of endotoxin in 390 Swedish homes: determinants and the risk for respiratory symptoms in children
Creators: Syed Moniruzzaman - Public Health Sciences, Karlstad University, Karlstad, Sweden. syed.moniruzzaman@kau.se
Linda Hägerhed Engman
Peter James
Torben Sigsgaard
Peter S Thorne
Jan Sundell
Carl-Gustaf Bornehag
Resource Type: Journal article
Publication Details: International journal of environmental health research, Vol.22(1), pp.22-36
Publisher: England
DOI: 10.1080/09603123.2011.588322
PMID: 21707246
ISSN: 0960-3123
eISSN: 1369-1619
Language: English
Date published: 2012
Academic Unit: Civil and Environmental Engineering; Occupational and Environmental Health
Record Identifier: 9983997447502771

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