Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women

Alexis E Duncan; Rosalind J Neuman; John R Kramer; Samuel Kuperman; Victor M Hesselbrock; Kathleen Keenan Bucholz

doi:10.1016/j.drugalcdep.2006.01.005

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Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women

Journal article

Peer reviewed

Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women

Alexis E Duncan, Rosalind J Neuman, John R Kramer, Samuel Kuperman, Victor M Hesselbrock and Kathleen Keenan Bucholz

Drug and alcohol dependence, Vol.84(1), pp.122-132

2006

DOI: 10.1016/j.drugalcdep.2006.01.005

PMID: 16455211

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Abstract

Previous work from our group revealed two groups of women with bulimia nervosa (BN), one with, and one without alcohol dependence (AD). The current study sought to determine whether women with lifetime BN and AD (BN+AD+) were more similar to women with BN and no AD (BN+AD−) or to women with AD and no BN (BN−AD+) in terms of lifetime psychiatric comorbidity and psychological functioning. Data on BN and AD from 407 female relatives in a family study of alcoholism were used to create three mutually exclusive groups: BN+AD+ ( n = 30), BN+AD− ( n = 55), and BN−AD+ ( n = 322). Bivariate analyses revealed fewer differences between BN+AD+ and BN−AD+ women than between BN+AD+ and BN+AD− women. BN+AD+ women were more likely than BN+AD− women to have drug dependence, conduct disorder, and suicidality, and were more likely to have major depression, lower GAF scores, and to engage in unsafe sex than both BN+AD− and BN−AD+ women. After adjusting for other psychopathology and demographic variables, BN+AD+ women were more likely than BN+AD− women to have major depression, drug dependence, and tobacco dependence and more likely than BN−AD+ women to have major depression and obsessive-compulsive disorder. These results suggest that BN+AD+ women exhibit more severe psychopathology than either BN+AD− or BN−AD+ women and may represent a distinct subgroup within bulimia nervosa or alcohol dependence.

Alcohol dependence

COGA

Comorbidity

Bulimia nervosa

Details

Title: Subtitle: Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women
Creators: Alexis E Duncan - Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States
Rosalind J Neuman - Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States
John R Kramer - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, United States
Samuel Kuperman - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, United States
Victor M Hesselbrock - Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT, United States
Kathleen Keenan Bucholz - Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States
Resource Type: Journal article
Publication Details: Drug and alcohol dependence, Vol.84(1), pp.122-132
DOI: 10.1016/j.drugalcdep.2006.01.005
PMID: 16455211
NLM abbreviation: Drug Alcohol Depend
ISSN: 0376-8716
eISSN: 1879-0046
Publisher: Elsevier Ireland Ltd
Language: English
Date published: 2006
Academic Unit: Psychiatry; Stead Family Department of Pediatrics
Record Identifier: 9984004184302771

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