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Lifetime substance misuse and 5-year incidence rates of emergent health problems among middle-aged adults
Journal article   Open access   Peer reviewed

Lifetime substance misuse and 5-year incidence rates of emergent health problems among middle-aged adults

Kristin M Caspers, Rebecca Yucuis, Lowell M McKirgan, Ruth Spinks and Stephan Arndt
Journal of addictive diseases, Vol.28(4), pp.320-331
10/2009
DOI: 10.1080/10550880903182796
PMCID: PMC2824908
PMID: 20155602
url
https://www.ncbi.nlm.nih.gov/pmc/articles/2824908View
Open Access

Abstract

Understanding the impact of prior substance misuse on emergent health problems is important to the implementation of effective preventive care. This study examined the 5-year incidence rates using a sample of middle-aged adult adoptees (N = 309, mean(age) = 44.32, standard deviation(age) = 7.28). Subjects reported on health problems at two waves of study. DSM-IV diagnoses of substance misuse were obtained using a semi-structured diagnostic interview. Finally, health services utilization and perceived health status were collected. Lifetime diagnoses of marijuana and other non-marijuana substance misuse significantly predicted new occurrences of cardiovascular and metabolic disease. Alcohol misuse predicted earlier onset of cardiovascular disease among men. Marijuana and other non-marijuana drugs predicted earlier onset of cardiovascular disease for men and women. Finally, marijuana and other non-marijuana drugs predicted earlier onset of metabolic disease among men. Substance misuse did not predict health services utilization despite higher rates of disease. These findings emphasize the need to assess lifetime substance misuse when evaluating health risks associated with use.
Adoption Adult Cardiovascular Diseases - complications Cardiovascular Diseases - epidemiology Chronic Disease - epidemiology Comorbidity Female Health Services - statistics & numerical data Health Status Humans Incidence Interview, Psychological Male Metabolic Diseases - complications Metabolic Diseases - epidemiology Middle Aged Proportional Hazards Models Sex Distribution Substance-Related Disorders - complications Substance-Related Disorders - diagnosis Substance-Related Disorders - epidemiology United States - epidemiology

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