Journal article
Limb segment load inhibits post activation depression of soleus H-reflex in humans
Clinical neurophysiology, Vol.123(9), pp.1836-1845
09/01/2012
DOI: 10.1016/j.clinph.2012.02.068
PMCID: PMC3380139
PMID: 22418592
Abstract
Objective: We investigated the effect of various doses of limb segment load on soleus H-reflex amplitude and post activation depression in healthy individuals. We also explored the influence of limb segment load on spinal circuitry in one individual with chronic SCI.
Methods: Twenty-eight healthy adults and one SCI subject received compressive loads applied to the top of their knee at varied doses of load (10%, 25%, and 50% of the body weight). Soleus H-reflexes were measured before (baseline) and during the loading phase.
Results: There were no significant differences in H-reflex amplitudes during the 50% BW load-on phase as compared to either baseline session or the load-off phase. However, the post activation depression was decreased over 9% (p < 0.05) during the load-on phase compared to the load-off phase and scaled according to load (50% > 25% > 10%). The post activation depression ratio also appears less responsive to varying loads after chronic SCI.
Conclusions: Limb segment load decreases post-activation depression in humans. These findings suggest that the mechanism associated with post activation depression is modulated by limb segment load, and may be influenced by spinal reorganization after SCI.
Significance: Future studies will determine if various levels of spasticity modulate the response of limb segment load on post activation depression in those with acute and chronic SCI. Published by Elsevier Ireland Ltd. on behalf of International Federation of Clinical Neurophysiology.
Details
- Title: Subtitle
- Limb segment load inhibits post activation depression of soleus H-reflex in humans
- Creators
- Shih-Chiao Tseng - Roy J. and Lucille A. Carver College of MedicineRichard K. Shields - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Clinical neurophysiology, Vol.123(9), pp.1836-1845
- Publisher
- Elsevier
- DOI
- 10.1016/j.clinph.2012.02.068
- PMID
- 22418592
- PMCID
- PMC3380139
- ISSN
- 1388-2457
- eISSN
- 1872-8952
- Number of pages
- 10
- Grant note
- Craig H. Neilsen Foundation R01HD062507 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) R01HD062507 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Department of Veterans Affairs; US Department of Veterans Affairs
- Language
- English
- Date published
- 09/01/2012
- Academic Unit
- Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984295053302771
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