Journal article
Linac radiosurgery for benign meningiomas
International journal of radiation oncology, biology, physics, Vol.43(2), pp.321-327
1999
DOI: 10.1016/S0360-3016(98)00391-5
PMID: 10030256
Abstract
Purpose: To review outcomes for patients treated with linac radiosurgery for benign meningiomas.
Methods and Materials: Between January 1989 and July 1997, 70 patients with 76 meningiomas were treated with LINAC-based radiosurgery. In 38 patients, radiosurgery was the initial treatment. In 32 patients, radiosurgery followed surgery or conventional radiotherapy. The average treatment volume was 10.0 cm
3 (range, 0.6 to 28.6 cm
3). The mean peripheral dose was 12.7 Gy (range, 10 to 20 Gy). The mean clinical follow-up period was 23 months. No patient was lost to follow-up.
Results: No lesions enlarged during the follow-up period; of 48 lesions in patients who had follow-up for at least one year and hence had follow-up imaging, 27 tumors remained unchanged and 21 tumors were reduced in size. Two patients experienced transient radiation-induced neurological deficits. One was treated with surgical excision of the tumor; the other responded to prolonged steroid therapy. Both patients, treated early in our experience, received doses higher than we would currently recommend.
Conclusions: Early results suggest that stereotactic radiosurgery is an effective treatment for meningiomas. Long-term follow-up will be necessary to fully evaluate its efficacy.
Details
- Title: Subtitle
- Linac radiosurgery for benign meningiomas
- Creators
- David H Shafron - Department of Neurosurgery, University of Florida College of Medicine, Gainesville, Florida, USAWilliam A Friedman - Department of Neurosurgery, University of Florida College of Medicine, Gainesville, Florida, USAJohn M Buatti - Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USAFrank J Bova - Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USAWilliam M Mendenhall - Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA
- Resource Type
- Journal article
- Publication Details
- International journal of radiation oncology, biology, physics, Vol.43(2), pp.321-327
- DOI
- 10.1016/S0360-3016(98)00391-5
- PMID
- 10030256
- NLM abbreviation
- Int J Radiat Oncol Biol Phys
- ISSN
- 0360-3016
- eISSN
- 1879-355X
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1999
- Academic Unit
- Radiation Oncology; Neurosurgery; Otolaryngology
- Record Identifier
- 9984040314202771
Metrics
8 Record Views