Journal article
Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition
International journal of psychophysiology, Vol.53(2), pp.75-90
2004
DOI: 10.1016/j.ijpsycho.2004.02.004
PMID: 15210286
Abstract
Event-related oscillations (ERO) offer an alternative theoretical and methodological approach to the analysis of event-related EEG responses. The P300 event-related potential (ERP) is elicited through the superposition of the delta (1–3 Hz) and theta (3–7 Hz) band oscillatory responses. The cholinergic neurotransmitter system has a key function in modulating excitatory post-synaptic potentials caused by glutamate, and therefore influences P300 generation and the underlying oscillatory responses. Here we report significant linkage and linkage disequilibrium between target case frontal theta band, visual evoked brain oscillations and a single nucleotide polymorphism (SNP) from the cholinergic muscarinic receptor gene (
Details
- Title: Subtitle
- Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition
- Creators
- Kevin A Jones - Department of Psychiatry, Neurodynamics Laboratory, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USABernice Porjesz - Department of Psychiatry, Neurodynamics Laboratory, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USALaura Almasy - Southwest Foundation for Biomedical Research, San Antonio, TX, USALaura Bierut - Washington University School of Medicine, St. Louis, MO, USAAlison Goate - Washington University School of Medicine, St. Louis, MO, USAJen C Wang - Washington University School of Medicine, St. Louis, MO, USADanielle M Dick - Washington University School of Medicine, St. Louis, MO, USAAnthony Hinrichs - Washington University School of Medicine, St. Louis, MO, USAJennifer Kwon - Washington University School of Medicine, St. Louis, MO, USAJohn P Rice - Washington University School of Medicine, St. Louis, MO, USAJohn Rohrbaugh - Washington University School of Medicine, St. Louis, MO, USAHeather Stock - Washington University School of Medicine, St. Louis, MO, USAWilliam Wu - Washington University School of Medicine, St. Louis, MO, USALance O Bauer - University of Connecticut, Farmington, CT, USADavid B Chorlian - Department of Psychiatry, Neurodynamics Laboratory, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USARaymond R Crowe - University of Iowa, Psychiatry Research, Iowa City, IA, USAHoward J Edenberg - Indiana University School of Medicine, Indianapolis, IN, USATatiana Foroud - Indiana University School of Medicine, Indianapolis, IN, USAVictor Hesselbrock - University of Connecticut, Farmington, CT, USASamuel Kuperman - University of Iowa, Psychiatry Research, Iowa City, IA, USAJohn Nurnberger Jr - Indiana University School of Medicine, Indianapolis, IN, USASean J O'Connor - Indiana University School of Medicine, Indianapolis, IN, USAMarc A Schuckit - University of California, San Diego, CA, USAArthur T Stimus - Department of Psychiatry, Neurodynamics Laboratory, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USAJay A Tischfield - Rutgers University, Piscataway, NJ, USATheodore Reich - Washington University School of Medicine, St. Louis, MO, USAHenri Begleiter - Department of Psychiatry, Neurodynamics Laboratory, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USA
- Resource Type
- Journal article
- Publication Details
- International journal of psychophysiology, Vol.53(2), pp.75-90
- Publisher
- Elsevier B.V
- DOI
- 10.1016/j.ijpsycho.2004.02.004
- PMID
- 15210286
- ISSN
- 0167-8760
- eISSN
- 1872-7697
- Language
- English
- Date published
- 2004
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984004082402771
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