Journal article
Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11
Genomics (San Diego, Calif.), Vol.14(4), pp.988-994
1992
DOI: 10.1016/S0888-7543(05)80121-1
PMID: 1478677
Abstract
Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.
Details
- Title: Subtitle
- Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11
- Creators
- W.J Kimberling - Boys TownC.G Möller - Linköping UniversityS Davenport - Sensory (United States)I.A Priluck - Creighton UniversityP.H Beighton - University of Cape TownJ Greenberg - University of Cape TownW Reardon - University College LondonM.D WestonJ.B Kenyon - Boys TownJ.A Grunkemeyer - Boys TownS Pieke Dahl - Boys Town National Research HospitalL.D Overbeck - Boys TownD.J Blackwood - Boys TownA.M Brower - Boys TownD.M Hoover - Boys TownP Rowland - St. Joseph's School for Deaf BoysR.J.H Smith - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Genomics (San Diego, Calif.), Vol.14(4), pp.988-994
- DOI
- 10.1016/S0888-7543(05)80121-1
- PMID
- 1478677
- NLM abbreviation
- Genomics
- ISSN
- 0888-7543
- eISSN
- 1089-8646
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1992
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Molecular Physiology and Biophysics; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Otolaryngology; Internal Medicine
- Record Identifier
- 9984256839502771
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