Journal article
Linking mind and brain in the study of mental illnesses: a project for a scientific psychopathology
Science (American Association for the Advancement of Science), Vol.275(5306), pp.1586-1593
03/14/1997
DOI: 10.1126/science.275.5306.1586
PMID: 9054346
Abstract
Brain research on mental illnesses has made substantial advances in recent years, supported by conceptual and technological developments in cognitive neuroscience. Brain-based cognitive models of illnesses such as schizophrenia and depression have been tested with a variety of techniques, including the lesion method, tract tracing, neuroimaging, animal modeling, single-cell recording, electrophysiology, neuropsychology, and experimental cognitive psychology. A relatively sophisticated picture is emerging that conceptualizes mental illnesses as disorders of mind arising in the brain. Convergent data using multiple neuroscience techniques indicate that the neural mechanisms of mental illnesses can be understood as dysfunctions in specific neural circuits and that their functions and dysfunctions can be influenced or altered by a variety of cognitive and pharmacological factors.
Details
- Title: Subtitle
- Linking mind and brain in the study of mental illnesses: a project for a scientific psychopathology
- Creators
- N C Andreasen - Mental Health Clinical Research Center, The University of Iowa Hospitals and Clinics and College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Science (American Association for the Advancement of Science), Vol.275(5306), pp.1586-1593
- Publisher
- United States
- DOI
- 10.1126/science.275.5306.1586
- PMID
- 9054346
- ISSN
- 0036-8075
- eISSN
- 1095-9203
- Grant note
- MH31593 / NIMH NIH HHS MH40856 / NIMH NIH HHS MH-CRC43271 / NIMH NIH HHS
- Language
- English
- Date published
- 03/14/1997
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003902002771
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