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Liposomal Bupivacaine Infiltration for Post-procedural Analgesia Following Interventional Procedures for Vascular Anomalies
Journal article   Open access   Peer reviewed

Liposomal Bupivacaine Infiltration for Post-procedural Analgesia Following Interventional Procedures for Vascular Anomalies

Mohammad A. Amarneh, Kyung Kim, Raja Shaikh, Cindy L. Kerr, Horacio Padua, Gulraiz Chaudry and Ahmad I. Alomari
Journal of vascular surgery cases and innovative techniques, Vol.11(4), 101796
08/2025
DOI: 10.1016/j.jvscit.2025.101796
PMCID: PMC12138537
PMID: 40475273
url
https://doi.org/10.1016/j.jvscit.2025.101796View
Published (Version of record) Open Access

Abstract

To describe the use and assess the safety of Liposomal Bupivacaine (LB) infiltration for prolonged post-procedural analgesia following procedures to treat vascular anomalies. This is a single-center prospective study. Consecutive patients aged 6 years or older undergoing painful interventions for vascular anomalies were included. Data collected included patient demographics, diagnosis, procedure details, LB dosage, peri-procedural pain levels, side effects, and the use of additional analgesics. Follow-up extended through post-procedural day 5. LB was utilized in 26 procedures in 24 patients with mean age of 17 years (range 6-33, median 17.5). One patient was excluded due to lack of follow-up. Twenty patients did not require any pain medication in the recovery unit. The mean pain level was 4, 2, 2, 2 on POD 1, 2, 3, and 5, respectively. No side effects were noted. LB proved to be a safe and likely effective local anesthetic agent, providing prolonged post-procedural analgesia for patients undergoing painful treatments for vascular anomalies. -Liposomal bupivacaine (LB) is a long-acting local anesthetic designed to slowly release bupivacaine gradually for extended pain relief up to 96 hours.-LB was used in 26 painful procedures for vascular anomalies on 24 pediatric and adult patients with no reported adverse events.-Patients followed up to 5 days, reported low pain levels and mild impact on mood, activity, ability to walk, and sleep.
 Liposomal Bupivacaine local anesthesia vascular anomalies

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