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Listeria monocytogenes infection in a patient treated with methotrexate for rheumatoid arthritis
Journal article   Peer reviewed

Listeria monocytogenes infection in a patient treated with methotrexate for rheumatoid arthritis

M M McCambridge, S A Vogelgesang and C F Ockenhouse
Journal of rheumatology, Vol.22(4), pp.786-787
04/1995
PMID: 7791185

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Abstract

We describe a patient with rheumatoid arthritis who developed bacteremia from Listeria monocytogenes after treatment with low dose oral pulse methotrexate. We discuss possible immunologic mechanisms for susceptibility to Listeria infections. As the elderly population increases with more frequent use of immunosuppressive medications, clinical suspicion must be maintained to correctly diagnose and treat infections such as Listeria.
Methotrexate - adverse effects Bacteremia - chemically induced Time Factors Arthritis, Rheumatoid - drug therapy Humans Aged, 80 and over Listeriosis - chemically induced Male Methotrexate - administration & dosage Aged Methotrexate - therapeutic use

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