Journal article
Liver transplantation and autoimmune hepatitis
Intractable and rare disease research, Vol.4(1), pp.33-38
02/01/2015
DOI: 10.5582/irdr.2014.01034
PMCID: PMC4322593
PMID: 25674386
Abstract
Liver Transplantation (LT) is an effective treatment for patients with end-stage liver disease including autoimmune hepatitis (AIH). Indication for LT for AIH does not differ basically from other liver diseases including both acute and chronic types of disease progression, although it is reported to be an infrequent indication for LT worldwide due to the therapeutic advances of immunosuppression. The outcome following LT is feasible, with current patient and graft survival exceeding 75% at 5 years. Recurrent and
de-novo
AIH posttranslant has also been reported; and this seems to have important clinical implications because its management differs from the standard treatment for allograft rejection. In this review, we discuss the characteristics of AIH, focusing on the indication for LT and issues raised following LT.
Details
- Title: Subtitle
- Liver transplantation and autoimmune hepatitis
- Creators
- Tomohiro Tanaka - University of Tokyo HospitalYasuhiko Sugawara - The University of TokyoNorihiro Kokudo - The University of Tokyo
- Resource Type
- Journal article
- Publication Details
- Intractable and rare disease research, Vol.4(1), pp.33-38
- Publisher
- International Research and Cooperation Association for Bio & Socio-Sciences Advancement
- DOI
- 10.5582/irdr.2014.01034
- PMID
- 25674386
- PMCID
- PMC4322593
- ISSN
- 2186-3644
- eISSN
- 2186-361X
- Language
- English
- Date published
- 02/01/2015
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984359781202771
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