Journal article
Localization of two new DNA markers on the linkage map of human chromosome 6q
Cytogenetics and cell genetics, Vol.60(3-4), pp.216-218
1992
DOI: 10.1159/000133342
PMID: 1354595
Abstract
Recently, an autosomal homolog of the dystrophin gene (DMDL) was identified on chromosome 6q24. As part of our analysis of the DMDL locus, we endeavoured to isolate DNA markers to further define the genetic map of this region. We have isolated and characterized two new genetic markers in the region of the DMDL locus, the RFLP D6S129 and a (CA)n dinucleotide repeat polymorphism within the DMDL gene itself and have positioned them on the existing genetic map of chromosome 6q. These markers will be important in testing the hypothesis that the DMDL gene is the locus responsible for autosomal forms of neuromuscular disease.
Details
- Title: Subtitle
- Localization of two new DNA markers on the linkage map of human chromosome 6q
- Creators
- B. C BYTH - Univ. Iowa, John Radcliffe hosp., molecular genetics group, Oxford, United KingdomD. R LOVE - Univ. Iowa, John Radcliffe hosp., molecular genetics group, Oxford, United KingdomJ. C MURRAY - Univ. Iowa, John Radcliffe hosp., molecular genetics group, Oxford, United KingdomK. E DAVIES - Univ. Iowa, John Radcliffe hosp., molecular genetics group, Oxford, United Kingdom
- Resource Type
- Journal article
- Publication Details
- Cytogenetics and cell genetics, Vol.60(3-4), pp.216-218
- DOI
- 10.1159/000133342
- PMID
- 1354595
- NLM abbreviation
- Cytogenet Cell Genet
- ISSN
- 0301-0171
- eISSN
- 1424-859X
- Publisher
- Karger; Freiburg; Basel; Paris
- Language
- English
- Date published
- 1992
- Academic Unit
- Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984025327002771
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