Journal article
Locally advanced anaplastic pancreatic adenocarcinoma with initial response to FOLFIRINOX and rapid progression after five months
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol.12(1), pp.35-38
01/2012
DOI: 10.1016/j.pan.2012.01.001
PMID: 22487471
Abstract
Anaplastic pancreatic carcinoma (APC) is a rare, aggressive variant of pancreatic ductal adenocarcinoma. Surgery is the preferred treatment whenever possible, however APC is often unresectable at presentation and prognosis remains poor. We present a case of APC which showed a marked initial response to FOLFIRINOX with decreased size and increased cystic change, however then rapidly progressed with innumerable hepatic metastases after five months of FOLFIRINOX treatment. Although there is limited data on use of FOLFIRINOX in locally advanced pancreatic adenocarcinoma, it remains an attractive option in comparison to radiotherapy and 5-fluorouracil.
Details
- Title: Subtitle
- Locally advanced anaplastic pancreatic adenocarcinoma with initial response to FOLFIRINOX and rapid progression after five months
- Creators
- Atul B Shinagare - Department of Imaging, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. ashinagare@partners.orgNikhil H RamaiyaAndrew M BellizziRobert J Mayer
- Resource Type
- Journal article
- Publication Details
- Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol.12(1), pp.35-38
- Publisher
- Switzerland
- DOI
- 10.1016/j.pan.2012.01.001
- PMID
- 22487471
- ISSN
- 1424-3903
- eISSN
- 1424-3911
- Language
- English
- Date published
- 01/2012
- Academic Unit
- Pathology
- Record Identifier
- 9984046823302771
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