Journal article
Long-Term Efficacy of Selective Laser Trabeculoplasty in Patients on Prostaglandin Therapy
Klinische Monatsblätter für Augenheilkunde, Vol.231(4), pp.351-356
04/01/2014
DOI: 10.1055/s-0034-1368218
PMID: 24771166
Abstract
Abstract
Background:
The aim of the study was to analyse the efficacy of selective laser
trabeculoplasty in patients on medical therapy and to evaluate a possible influence of
prostaglandin therapy on intraocular pressure reduction.
Patients and Methods:
A
retrospective chart review was undertaken of patients with ocular hypertension or open angle
glaucoma who underwent selective laser trabeculoplasty between 3/2008 and 12/2010. Data were
collected preoperatively, on the day of intervention, 1 day, 1 month and then every 3 months
post selective laser trabeculoplasty. The main outcome measure was mean intraocular pressure
reduction.
Results:
109 eyes (76 on prostaglandins) were included. Mean preoperative
intraocular pressure was 22.3 ± 4.5 mmHg (prostaglandin naïve) and 19.2 ± 4.8 mmHg (on
prostaglandin) (p = 0.003). Up to 1 year follow-up, intraocular pressure was statistically
significantly reduced in both groups (p ≤ 0.019). Eyes with a higher preoperative intraocular
pressure had a greater pressure reduction (Spearman rho = 0.387, p = 0.002). Eyes naïve to
prostaglandins initially had a greater reduction in intraocular pressure, although after 1 year
of follow-up the difference was no longer statistically significant.
Conclusions:
Selective laser trabeculoplasty significantly reduces intraocular pressure in patients already
on medical therapy. A sustained influence of prostaglandin therapy on the efficacy of selective
laser trabeculoplasty was not found.
Details
- Title: Subtitle
- Long-Term Efficacy of Selective Laser Trabeculoplasty in Patients on Prostaglandin Therapy
- Creators
- C. Hirn - Triemli HospitalS. Zehnder - Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland (Institution Chairman: Klara Landau)G. Bauer - Kantonsspital AarauG. P. Jaggi - Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland (Institution Chairman: Klara Landau)M. Töteberg-Harms - Case Western Reserve UniversityS. A. Zweifel - Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland (Institution Chairman: Klara Landau)D. J. Lindegger - Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland (Institution Chairman: Klara Landau)J. Funk - Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland (Institution Chairman: Klara Landau)
- Resource Type
- Journal article
- Publication Details
- Klinische Monatsblätter für Augenheilkunde, Vol.231(4), pp.351-356
- Publisher
- Georg Thieme Verlag KG
- DOI
- 10.1055/s-0034-1368218
- PMID
- 24771166
- ISSN
- 0023-2165
- eISSN
- 1439-3999
- Language
- English
- Date published
- 04/01/2014
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984696723802771
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