Journal article
Long-Term Illness in Adults Hospitalized for Respiratory Syncytial Virus Disease, United States, February 2022-September 2023
Emerging infectious diseases, Vol.31(14 Suppl), pp.S20-S29
12/2025
DOI: 10.3201/eid3114.241982
PMID: 41570181
Abstract
Respiratory syncytial virus (RSV) can cause severe illness, but little is known about long-term consequences in hospitalized adults. We surveyed adults (>18 years of age) who survived hospitalization for RSV or COVID-19 during February 2022-September 2023 about physical functioning and quality of life; surveys were conducted 6-12 months after hospitalization. We compared outcomes after RSV hospitalization by age (<60 vs. >60 years) and to those hospitalized for COVID-19 by using multivariable regression models. Among 146 adults hospitalized with RSV, 27.4% reported severe breathlessness and 21.9% poor quality of life at follow-up. Few differences were seen in posthospital illness by age. After adjustment, participants with RSV had 1.81 (95% CI 1.08-3.04) times increased odds of worse dyspnea than did those with COVID-19. Participants reported functional and quality of life impairments after RSV hospitalization, regardless of age, and a postdischarge sequelae constellation similar to that for those hospitalized for COVID-19.Respiratory syncytial virus (RSV) can cause severe illness, but little is known about long-term consequences in hospitalized adults. We surveyed adults (>18 years of age) who survived hospitalization for RSV or COVID-19 during February 2022-September 2023 about physical functioning and quality of life; surveys were conducted 6-12 months after hospitalization. We compared outcomes after RSV hospitalization by age (<60 vs. >60 years) and to those hospitalized for COVID-19 by using multivariable regression models. Among 146 adults hospitalized with RSV, 27.4% reported severe breathlessness and 21.9% poor quality of life at follow-up. Few differences were seen in posthospital illness by age. After adjustment, participants with RSV had 1.81 (95% CI 1.08-3.04) times increased odds of worse dyspnea than did those with COVID-19. Participants reported functional and quality of life impairments after RSV hospitalization, regardless of age, and a postdischarge sequelae constellation similar to that for those hospitalized for COVID-19.
Details
- Title: Subtitle
- Long-Term Illness in Adults Hospitalized for Respiratory Syncytial Virus Disease, United States, February 2022-September 2023
- Creators
- Aleda M LeisKelsey N WomackCourtney MaxcyEllen CaldwellCaroline ChengSydney A CornelisonDiya SurieFatimah S DawoodSharon SaydahManjusha GaglaniCristie ColumbusAbhijit DuggalLaurence W BusseLaurynn M GilesIvana A VaughnIthan D PeltanDavid N HagerAmira MohamedMatthew C ExlineAkram KhanJennifer G WilsonJarrod S MosierSteven Y ChangAdit A GindeNicholas M MohrChristopher MallowEstelle S HarrisNicholas J JohnsonKevin W GibbsJennie H KwonBasmah SafdarEmily T MartinWesley H SelfCatherine L HoughJin H HanInvestigating Respiratory Viruses in the Acutely Ill (IVY) Network
- Resource Type
- Journal article
- Publication Details
- Emerging infectious diseases, Vol.31(14 Suppl), pp.S20-S29
- DOI
- 10.3201/eid3114.241982
- PMID
- 41570181
- NLM abbreviation
- Emerg Infect Dis
- ISSN
- 1080-6059
- eISSN
- 1080-6059
- Language
- English
- Date published
- 12/2025
- Academic Unit
- Epidemiology; Emergency Medicine; Anesthesia; Injury Prevention Research Center
- Record Identifier
- 9985130239302771
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