Journal article
Long-Term Outcomes of Urgency-Frequency Syndrome Due to Painful Bladder Syndrome Treated With Sacral Neuromodulation and Analysis of Failures
The Journal of urology, Vol.183(1), pp.173-176
01/01/2010
DOI: 10.1016/j.juro.2009.08.142
PMID: 19913835
Abstract
Purpose: We present our long-term experience with sacral neuromodulation devices placed in patients with painful bladder syndrome to determine whether the benefit decreases over time.
Materials and Methods: Between January 2000 and July 2004, 32 women and 7 men with interstitial cystitis/painful bladder syndrome in whom previous conventional therapy failed underwent sacral neuromodulation test stimulation. Before 2003 a percutaneous test lead was placed in the clinic setting. After 2003 a quadripolar permanent lead was placed in the operating room. Permanent generators were implanted if the patient had more than 50% relief from the presenting complaint, which was defined as urinary or pelvic pain, urgency, or urinary frequency. Long-term outcomes included battery depletion, device malfunction, infection or loss of benefit as well as any change in need for medications.
Results: Of 39 patients 22 went from test stimulation to permanent generator implantation. There were significant differences in short-term but not long-term outcomes between the 2 methods of test stimulation. Of 33 patients undergoing percutaneous nerve evaluation 13 (39.4%) met the criteria for permanent generator implantation, while 9 of 11 (81.8%) evaluated with the quadripolar lead met these criteria (p = 0.015). Long-term success between the groups was similar at 92.3% (12 of 13) vs 77.8% (7 of 9) (p = 0.329) during an average followup of 59.9 months. Eleven (50.0%) devices required explantation. Of 22 patients 3 (13.6%) lost benefit over time.
Conclusions: These patients appear to respond best to permanent quadripolar lead placement but long-term results do not appear to be independently affected by the method of test stimulation. Loss of benefit over time is not common.
Details
- Title: Subtitle
- Long-Term Outcomes of Urgency-Frequency Syndrome Due to Painful Bladder Syndrome Treated With Sacral Neuromodulation and Analysis of Failures
- Creators
- Charles R. Powell - University of IowaKarl J. Kreder - University of Iowa
- Resource Type
- Journal article
- Publication Details
- The Journal of urology, Vol.183(1), pp.173-176
- Publisher
- Elsevier
- DOI
- 10.1016/j.juro.2009.08.142
- PMID
- 19913835
- ISSN
- 0022-5347
- eISSN
- 1527-3792
- Number of pages
- 4
- Grant note
- Pfizer Medtronics
- Language
- English
- Date published
- 01/01/2010
- Academic Unit
- Obstetrics and Gynecology; Urology
- Record Identifier
- 9984383306802771
Metrics
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