Long-term functional and quality of life outcomes of patients after repair of large perianal skin defects for Paget's and Bowen's disease

Alissa Conklin; Imran Hassan; Heidi K Chua; E Dawn Wietfeldt; Dirk R Larson; Kristine A Thomsen; Sanhat Nivatvongs

doi:10.1007/s11605-009-0822-x

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Long-term functional and quality of life outcomes of patients after repair of large perianal skin defects for Paget's and Bowen's disease

Journal article

Peer reviewed

Long-term functional and quality of life outcomes of patients after repair of large perianal skin defects for Paget's and Bowen's disease

Alissa Conklin, Imran Hassan, Heidi K Chua, E Dawn Wietfeldt, Dirk R Larson, Kristine A Thomsen and Sanhat Nivatvongs

Journal of gastrointestinal surgery, Vol.13(5), pp.951-955

05/2009

DOI: 10.1007/s11605-009-0822-x

PMID: 19224296

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Abstract

The assessment of long- term functional and quality of life outcomes of these patients following repair of large defects after surgical excision has not been reported. Between 1992 and 2004, at two institutions, 18 patients underwent repair of a perianal defect for Paget's disease (n = 8) or Bowen's disease (n = 10) and were alive with intestinal continuity at last follow-up. Patients were mailed the fecal incontinence quality of life scale (FIQL) and the SF-36. Fourteen patients (78%) responded. Median follow-up for responders was 5 years. Mean age was 65 years with 12 females. Subcutaneous skin flaps (11) and split-thickness skin grafts (three) were used to repair the perianal defects, which were circumferential in 11 patients (79%). Nine patients reported incontinence and completed the FIQL. The FIQL scores of patients reporting incontinence were lower for lifestyle, coping/behavior, and embarrassment but not significantly different for depression compared to patients without incontinence. SF-36 scores of the patients were not significantly different from the normative population. Functional results after repair of large perianal defects are acceptable and overall quality of life (QOL) is similar to the normative population although a large proportion of patients have some form of incontinence that impacts certain aspects of their QOL.

Paget Disease, Extramammary - surgery

Fecal Incontinence - epidemiology

Follow-Up Studies

Humans

Middle Aged

Anus Neoplasms - surgery

Male

Recovery of Function

Time Factors

Aged, 80 and over

Female

Surveys and Questionnaires

Anus Neoplasms - physiopathology

Skin Neoplasms - surgery

Skin Neoplasms - pathology

Bowen's Disease - physiopathology

Bowen's Disease - pathology

Treatment Outcome

Anus Neoplasms - pathology

Bowen's Disease - surgery

Skin Neoplasms - physiopathology

Paget Disease, Extramammary - physiopathology

Paget Disease, Extramammary - pathology

Fecal Incontinence - psychology

Quality of Life

Aged

Details

Title: Subtitle: Long-term functional and quality of life outcomes of patients after repair of large perianal skin defects for Paget's and Bowen's disease
Creators: Alissa Conklin - Department of Surgery, Southern Illinois University School of Medicine, Springfield, IL 62704, USA
Imran Hassan
Heidi K Chua
E Dawn Wietfeldt
Dirk R Larson
Kristine A Thomsen
Sanhat Nivatvongs
Resource Type: Journal article
Publication Details: Journal of gastrointestinal surgery, Vol.13(5), pp.951-955
Publisher: United States
DOI: 10.1007/s11605-009-0822-x
PMID: 19224296
ISSN: 1091-255X
eISSN: 1873-4626
Language: English
Date published: 05/2009
Academic Unit: Surgery
Record Identifier: 9984051574302771

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