Loop Diuretics-Analysis of Efficacy Data for the Perioperative Clinician

Archit Sharma; Sarat Kuppachi; Sudhakar Subramani; Anureet Walia; Jacob Thomas; Harish Ramakrishna

doi:10.1053/j.jvca.2019.10.035

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Loop Diuretics-Analysis of Efficacy Data for the Perioperative Clinician

Journal article

Peer reviewed

Loop Diuretics-Analysis of Efficacy Data for the Perioperative Clinician

Archit Sharma, Sarat Kuppachi, Sudhakar Subramani, Anureet Walia, Jacob Thomas and Harish Ramakrishna

Journal of cardiothoracic and vascular anesthesia, Vol.34(8), pp.2253-2259

08/01/2020

DOI: 10.1053/j.jvca.2019.10.035

PMID: 31879151

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Abstract

HEART FAILURE (HF) is one of the most common causes of hospitalization in the United States. Loop diuretics (LD) are the mainstay of treatment in the management of acute and chronic HF. Although they generally are effective in relieving symptoms and reducing congestion, LD have not been shown to significantly affect morbidity and mortality. The initial decongestion strategy for management of HF is likely to be an LD, with evidence suggesting that an initial "high-dose" strategy either by twice-daily bolus injection or by continuous infusion is likely to be more successful than an initial lower dose in respect to relief of symptoms but at the expense of increased worsening of renal function. This review focuses on the current state of evidence of different strategies related to the use of LD in the treatment of congestive symptoms in critically ill patients and presents a summary of the body of evidence regarding dosages, timing, and different diuretic agents. (C) 2019 Published by Elsevier Inc.

Anesthesiology

Cardiac & Cardiovascular Systems

Cardiovascular System & Cardiology

Life Sciences & Biomedicine

Peripheral Vascular Disease

Respiratory System

Science & Technology

Details

Title: Subtitle: Loop Diuretics-Analysis of Efficacy Data for the Perioperative Clinician
Creators: Archit Sharma - Roy J. and Lucille A. Carver College of Medicine
Sarat Kuppachi - University of Iowa Hospitals and Clinics
Sudhakar Subramani - Roy J. and Lucille A. Carver College of Medicine
Anureet Walia - Roy J. and Lucille A. Carver College of Medicine
Jacob Thomas - University of Iowa
Harish Ramakrishna - Mayo Clinic in Florida
Resource Type: Journal article
Publication Details: Journal of cardiothoracic and vascular anesthesia, Vol.34(8), pp.2253-2259
Publisher: Elsevier
DOI: 10.1053/j.jvca.2019.10.035
PMID: 31879151
ISSN: 1053-0770
eISSN: 1532-8422
Number of pages: 7
Language: English
Date published: 08/01/2020
Academic Unit: Psychiatry; Stead Family Department of Pediatrics; Anesthesia; Nephrology; Internal Medicine
Record Identifier: 9984295957402771

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