Low-frequency H-reflex depression in trained human soleus after spinal cord injury

Richard K SHIELDS; Shauna DUDLEY-JAVOROSKI; Preeti Deshpande Oza

doi:10.1016/j.neulet.2011.05.040

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Low-frequency H-reflex depression in trained human soleus after spinal cord injury

Journal article

Open access

Peer reviewed

Low-frequency H-reflex depression in trained human soleus after spinal cord injury

Richard K SHIELDS, Shauna DUDLEY-JAVOROSKI and Preeti Deshpande Oza

Neuroscience letters, Vol.499(2), pp.88-92

2011

DOI: 10.1016/j.neulet.2011.05.040

PMCID: PMC4034355

PMID: 21640787

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http://doi.org/10.1016/j.neulet.2011.05.040View

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Abstract

After spinal cord injury (SCI), widespread reorganization occurs within spinal reflex systems. Regular muscle activity may influence reorganization of spinal circuitry after SCI. The purpose of this study is to investigate the effects of long-term soleus training on H-reflex depression in humans after SCI. Seven subjects with acute (<7 weeks) SCI (AC group) underwent testing of H-reflex depression at several frequencies of repetitive stimulation. Eight subjects (including 3 from AC) stimulated one soleus muscle daily, leaving the other leg as an untrained within-subject control. Trained limb H-reflexes were assessed during year 1 (TR1) and year 2 (TR2) of training. Untrained limbs were tested during year 2 (UN). H-reflex amplitude was lower at 1, 2 and 5 Hz than at 0.1 or 0.2 Hz (p < 0.05). The pattern of depression differed between AC and UN (p < 0.05), but not between TR2 and UN (p > 0.05) despite significant adaptations in torque and fatigue resistance (p < 0.05). Three subjects who began training very early after SCI retained H-reflex post activation depression, suggesting that early intervention of daily muscular activity may be important.

Fundamental and applied biological sciences. Psychology

Vertebrates: nervous system and sense organs

Biological and medical sciences

Details

Title: Subtitle: Low-frequency H-reflex depression in trained human soleus after spinal cord injury
Creators: Richard K SHIELDS - Physical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, IA, United States
Shauna DUDLEY-JAVOROSKI - Physical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, IA, United States
Preeti Deshpande Oza - Physical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, IA, United States
Resource Type: Journal article
Publication Details: Neuroscience letters, Vol.499(2), pp.88-92
DOI: 10.1016/j.neulet.2011.05.040
PMID: 21640787
PMCID: PMC4034355
NLM abbreviation: Neurosci Lett
ISSN: 0304-3940
eISSN: 1872-7972
Publisher: Elsevier; Shannon
Grant note: name: NIH, award: R01NR010285, R01HD062507; DOI: 10.13039/100005191, name: Craig H. Neilsen Foundation
Language: English
Date published: 2011
Academic Unit: Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
Record Identifier: 9984047611002771

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