Journal article
Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population
European journal of nutrition, Vol.55(2), pp.699-711
03/2016
DOI: 10.1007/s00394-015-0890-5
PMID: 25832490
Abstract
Neurodevelopmental effects of omega-3 fatty acids and mercury from fish consumption have been characterized in children. In contrast, neurobehavioral outcomes associated with fish are not well studied in adults.
This study of avid seafood consumers on Long Island (NY, USA) sought to define associations between mercury, seafood consumption, omega-3 fatty acids and neurobehavioral outcomes.
A computer-based test system was used to assess neurobehavioral function. Blood total Hg (Hg) and omega-3 index were measured in 199 adult avid seafood eaters, who also completed the neurobehavioral assessment and an extensive food and fish frequency and demographic questionnaire.
For most of the outcomes considered, neither Hg nor omega-3 index was associated with neurobehavioral outcomes after adjustment for key confounding variables. Fish consumption, however, was associated with decreased odds of both self-reported fatigue (OR 0.85; 95 % CI 0.72, 1.01) and a constellation of neurologic symptoms (OR 0.79; 95 % CI 0.66, 0.96).
Results from our study provide little evidence that omega-3 fatty acids or Hg is associated with cognitive function in adult avid seafood consumers. Larger studies are needed to confirm our finding of associations between fish consumption and decreased self-reported fatigue and neurologic impairment.
Details
- Title: Subtitle
- Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population
- Creators
- Caterina Vacchi-Suzzi - Program in Public Health, Department of Preventive Medicine, Stony Brook University, Stony Brook, NY, 11794, USA. caterina.vacchi-suzzi@stonybrookmedicine.eduRoxanne Karimi - School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794, USADanielle Kruse - School of Medicine, Stony Brook University, Stony Brook, NY, 11794, USASusan M Silbernagel - Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, 98195, USAKeith E Levine - Trace Inorganics Department, Technologies for Industry and the Environment, RTI International, Research Triangle Park, NC, 27709, USADiane S Rohlman - Oregon Institute for Occupational Health Sciences, Oregon Health and Science University, Portland, OR, 97239, USAJaymie R Meliker - Program in Public Health, Department of Preventive Medicine, Stony Brook University, Stony Brook, NY, 11794, USA
- Resource Type
- Journal article
- Publication Details
- European journal of nutrition, Vol.55(2), pp.699-711
- DOI
- 10.1007/s00394-015-0890-5
- PMID
- 25832490
- NLM abbreviation
- Eur J Nutr
- ISSN
- 1436-6207
- eISSN
- 1436-6215
- Publisher
- Germany
- Grant note
- P30 ES005605 / NIEHS NIH HHS R01 ES019209 / NIEHS NIH HHS
- Language
- English
- Date published
- 03/2016
- Academic Unit
- Occupational and Environmental Health; International Programs; Injury Prevention Research Center
- Record Identifier
- 9983997453002771
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