Journal article
Lucibufagins. 2. Esters of 12-oxo-2.beta.,5.beta.,11.alpha.-trihydroxybufalin, the major defensive steroids of the firefly Photinus pyralis (Coleoptera: Lampyridae)
Journal of the American Chemical Society, Vol.101(11), pp.3055-3060
05/01/1979
DOI: 10.1021/ja00505a037
Abstract
Fireflies of the species Photinus pyralis (Coleoptera: Lampyridae) are shown to contain a group of closely related steroidal pyrones, named lucibufagins, which serve a defensive role. The five major steroids from this insect are characterized as esters (5, 6, 7, 11, 12) of 12-oxo-2β, 5β, 11 α-trihydroxybufalin (9), chiefly on the basis of detailed spectral analyses. Selective proton decoupling 13C NMR experiments played a key role in making these structural assignments. These insect-derived steroids are the first bufadienolides to be isolated and characterized from an invertebrate source. © 1979, American Chemical Society. All rights reserved.
Details
- Title: Subtitle
- Lucibufagins. 2. Esters of 12-oxo-2.beta.,5.beta.,11.alpha.-trihydroxybufalin, the major defensive steroids of the firefly Photinus pyralis (Coleoptera: Lampyridae)
- Creators
- Jerrold MeinwaldDavid F WiemerThomas Eisner
- Resource Type
- Journal article
- Publication Details
- Journal of the American Chemical Society, Vol.101(11), pp.3055-3060
- Publisher
- American Chemical Society
- DOI
- 10.1021/ja00505a037
- ISSN
- 0002-7863
- eISSN
- 1520-5126
- Language
- English
- Date published
- 05/01/1979
- Academic Unit
- Neuroscience and Pharmacology; Chemistry
- Record Identifier
- 9984217452602771
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