Journal article
Lymphomatous involvement of the central nervous system
Clinical radiology, Vol.71(6), pp.602-609
06/2016
DOI: 10.1016/j.crad.2016.02.006
PMID: 27038652
Abstract
Lymphoma may arise within the central nervous system (CNS), known as primary CNS lymphoma (PCNSL) or may involve the CNS secondary to systemic disease. Clinical features are non-specific. A provisional diagnosis of PCNSL can be made on imaging, potentially changing the management algorithm from neurosurgical resection to biopsy. PCNSL in immunocompetent patients generally presents late, is solid, is bright on diffusion weighted imaging and shows uniform enhancement. Contiguity with a cerebrospinal fluid (CSF) surface and perivascular enhancement are useful clues. Immunocompromised patients, on the other hand, present earlier and often have multiple, necrotic, haemorrhagic lesions with irregular or rim enhancement. Secondary CNS involvement predominantly affects the leptomeninges. This review illustrates the varied imaging features of CNS lymphoma, atypical presentations, and differential diagnoses.
Details
- Title: Subtitle
- Lymphomatous involvement of the central nervous system
- Creators
- G Bathla - Department of Radiology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA, USAA Hegde - Department of Radiology, Raffles Hospital, 585 North Bridge Drive, Singapore 188770, Singapore. Electronic address: amoghhegde7@gmail.com
- Resource Type
- Journal article
- Publication Details
- Clinical radiology, Vol.71(6), pp.602-609
- Publisher
- England
- DOI
- 10.1016/j.crad.2016.02.006
- PMID
- 27038652
- ISSN
- 0009-9260
- eISSN
- 1365-229X
- Language
- English
- Date published
- 06/2016
- Academic Unit
- Radiology
- Record Identifier
- 9984051777302771
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