MACROD2, an Original Cause of CIN?

Ning Jin; Mark E Burkard

doi:10.1158/2159-8290.CD-18-0674

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Journal article

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MACROD2, an Original Cause of CIN?

Ning Jin and Mark E Burkard

Cancer discovery, Vol.8(8), pp.921-923

08/2018

DOI: 10.1158/2159-8290.CD-18-0674

PMID: 30076143

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Abstract

Summary: The fundamental cause of chromosomal instability in colorectal cancer remains elusive. Genetic deletions of the MACROD2 tumor suppressor could play a major role.

Chromosomal Instability

Colorectal Neoplasms - genetics

DNA Repair Enzymes

Genes, Tumor Suppressor

Haploinsufficiency

Humans

Hydrolases

Poly (ADP-Ribose) Polymerase-1

Details

Title: Subtitle: MACROD2, an Original Cause of CIN?
Creators: Ning Jin - University of Wisconsin Carbone Cancer Center
Mark E Burkard - University of Wisconsin Carbone Cancer Center
Resource Type: Journal article
Publication Details: Cancer discovery, Vol.8(8), pp.921-923
DOI: 10.1158/2159-8290.CD-18-0674
PMID: 30076143
ISSN: 2159-8274
eISSN: 2159-8290
Grant note: T32 HL007899 / NHLBI NIH HHS P30 CA014520 / NCI NIH HHS
Language: English
Date published: 08/2018
Academic Unit: Internal Medicine
Record Identifier: 9984700654302771

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