MR fingerprinting of the prostate

Wei-Ching Lo; Ananya Panda; Yun Jiang; James Ahad; Vikas Gulani; Nicole Seiberlich

doi:10.1007/s10334-022-01012-8

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Journal article

Peer reviewed

MR fingerprinting of the prostate

Wei-Ching Lo, Ananya Panda, Yun Jiang, James Ahad, Vikas Gulani and Nicole Seiberlich

Magma (New York, N.Y.), Vol.35(4), pp.557-571

08/01/2022

DOI: 10.1007/s10334-022-01012-8

PMCID: PMC10288492

PMID: 35419668

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https://pmc.ncbi.nlm.nih.gov/articles/PMC10288492/pdf/nihms-1905951.pdfView

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Abstract

Multiparametric magnetic resonance imaging (mpMRI) has been adopted as the key tool for detection, localization, characterization, and risk stratification of patients suspected to have prostate cancer. Despite advantages over systematic biopsy, the interpretation of prostate mpMRI has limitations including a steep learning curve, leading to considerable interobserver variation. There is growing interest in clinical translation of quantitative imaging techniques for more objective lesion assessment. However, traditional mapping techniques are slow, precluding their use in the clinic. Magnetic resonance fingerprinting (MRF) is an efficient approach for quantitative maps of multiple tissue properties simultaneously. The T and T values obtained with MRF have been validated with phantom studies as well as in normal volunteers and patients. Studies have shown that MRF-derived T and T along with ADC values are all significant independent predictors in the differentiation between normal prostate tissue and prostate cancer, and hold promise in differentiating low and intermediate/high-grade cancers. This review seeks to introduce the basics of the prostate MRF technique, discuss the potential applications of prostate MRF for the characterization of prostate cancer, and describes ongoing areas of research.

Biopsy

Humans

Magnetic Resonance Imaging - methods

Male

Multiparametric Magnetic Resonance Imaging

Phantoms, Imaging

Prostate - diagnostic imaging

Prostate - pathology

Prostatic Neoplasms - diagnostic imaging

Prostatic Neoplasms - pathology

Details

Title: Subtitle: MR fingerprinting of the prostate
Creators: Wei-Ching Lo - Siemens (United States)
Ananya Panda - Mayo Clinic
Yun Jiang - University of Michigan
James Ahad - Case Western Reserve University
Vikas Gulani - University of Michigan
Nicole Seiberlich - Case Western Reserve University
Resource Type: Journal article
Publication Details: Magma (New York, N.Y.), Vol.35(4), pp.557-571
DOI: 10.1007/s10334-022-01012-8
PMID: 35419668
PMCID: PMC10288492
NLM abbreviation: MAGMA
ISSN: 0968-5243
eISSN: 1352-8661
Grant note: R37CA263583 / NCI NIH HHS R01 HL094557 / NHLBI NIH HHS T32 GM007250 / NIGMS NIH HHS T32GM007250 / NIH HHS F30CA23935 / NIH HHS F30 CA239355 / NCI NIH HHS R01CA208236 / NCI NIH HHS R01 CA208236 / NCI NIH HHS R37 CA263583 / NCI NIH HHS
Language: English
Date published: 08/01/2022
Academic Unit: Radiology
Record Identifier: 9984697726502771

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