MSH/ACTH 4–10 in men and women: Effects upon performance of an attention and memory task

Marcia M Ward; Curt A Sandman; Jack M George; Harvey Shulman

doi:10.1016/0031-9384(79)90228-2

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MSH/ACTH 4–10 in men and women: Effects upon performance of an attention and memory task

Journal article

Peer reviewed

MSH/ACTH 4–10 in men and women: Effects upon performance of an attention and memory task

Marcia M Ward, Curt A Sandman, Jack M George and Harvey Shulman

Physiology & behavior, Vol.22(4), pp.669-673

1979

DOI: 10.1016/0031-9384(79)90228-2

PMID: 225750

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Abstract

During two test sessions, twelve males and twelve females were subcutaneously administered 30 mg doses of MSH/ACTH4–10 or the diluent control solution in a double-blind, randomized, completely crossed design. The results indicated that in comparison to the control session, reaction time scores for the Sternberg item recognition task were significantly decreased after MSH/ACTH 4–10 administration. The reaction time scores were reduced by a nearly equal amount at each of four memory set sizes; this pattern of results suggests that the peptide exerts its effects on attention as opposed to memory. The decreased reaction times after peptide treatment occurred without a concomitant change in error rate. In addition, the order of treatment interacted significantly with the peptide treatment so that performance was apparently facilitated whether MSH/ACTH 4–10 administration preceded testing by an hour or by several days. Self-reported anxiety levels were not significantly affected by the peptide treatment. Males and females did not significantly differ on reaction time scores, error scores, or anxiety levels in the present study.

ACTH 4–10

Attention

Behavioral effects of peptides

Memory

MSH 4–10

Details

Title: Subtitle: MSH/ACTH 4–10 in men and women: Effects upon performance of an attention and memory task
Creators: Marcia M Ward
Curt A Sandman
Jack M George - Department of Medicine, The Ohio State University USA
Harvey Shulman - Department of Psychology, The Ohio State University, Columbus, OH 43210 USA
Resource Type: Journal article
Publication Details: Physiology & behavior, Vol.22(4), pp.669-673
DOI: 10.1016/0031-9384(79)90228-2
PMID: 225750
NLM abbreviation: Physiol Behav
ISSN: 0031-9384
eISSN: 1873-507X
Publisher: Elsevier Inc
Language: English
Date published: 1979
Academic Unit: Health Management and Policy
Record Identifier: 9984214699102771

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