Journal article
MSPT: an open-source motion simulator for proton therapy
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, Vol.1(3), 037001
2015
DOI: 10.1088/2057-1976/1/3/037001
Abstract
The dosimetric benefits of proton therapy may be greatly degraded when the tumor or organs move during the treatment. Hence, mitigation or adaptive methods have become topics of research interest. These techniques require dose computation on time-dependent patient geometry. Wedeveloped an open-source four-dimensional dose computation and evaluation software, Motion Simulator for Proton Therapy (MSPT), for the spot-scanning delivery technique. It aims at highlighting the impact of the patient motion during a treatment delivery by computing dose on the moving patient. The main interest of this simulator lies in the ability to render the impact of a predicted patient motion on a prescribed treatment plan. MSPT used proton pencil beam algorithm for dose computation, and the dose in patient geometry computed by MSPT was able to match that computed by the commercial treatment planning system. MSPT was able to render the impact of motion on patient data sets. This capability makes it an innovative research tool to evaluate and compare different methods of motion management or mitigation. The open-source feature makes it appealing, since it is intended to evolve, to be improved and to be the starting point of new research on patient motion in proton therapy.
Details
- Title: Subtitle
- MSPT: an open-source motion simulator for proton therapy
- Creators
- P Morel - Université Paris CitéR T Flynn - University of IowaE Gelover - University of IowaG Blin - University of BordeauxS Vialette - Université Paris CitéX Wu - University of IowaD Wang - University of Iowa
- Resource Type
- Journal article
- Publication Details
- BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, Vol.1(3), 037001
- DOI
- 10.1088/2057-1976/1/3/037001
- ISSN
- 2057-1976
- Grant note
- DOI: 10.13039/501100001665, name: Agence Nationale de la Recherche:, award: BIRDS JCJC SIMI 2-2010
- Language
- English
- Date published
- 2015
- Academic Unit
- Electrical and Computer Engineering; The Iowa Institute for Biomedical Imaging; Radiation Oncology
- Record Identifier
- 9984239419802771
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