Journal article
Maintenance of arterial pressure in infant rats during moderate and extreme thermal challenge
Developmental psychobiology, Vol.32(3), pp.169-176
04/1998
DOI: 10.1002/(SICI)1098-2302(199804)32:3<169::AID-DEV1>3.0.CO;2-M
PMID: 9553727
Abstract
It has recently been demonstrated in week-old rats that extreme cold challenges that lead to significant bodily cooling result in decreased cardiac rate. To determine whether pups are able to maintain arterial pressure in the face of decreasing cardiac rate in extreme cold, we measured blood pressure in unanesthetized week-old rats. Instrumented pups were thermally challenged and thermoregulatory and cardiovascular responses were monitored. Despite pronounced decreases in cardiac rate in the cold, pups were able to maintain mean arterial pressure (MAP), presumably by increasing peripheral resistance. At the lowest air temperature (17 degrees C) pups emitted ultrasonic vocalizations, and these emissions were accompanied by pulsatile increases in intraabdominal pressure (IAP) and MAP. We hypothesize that these pulsatile increases in IAP during extreme cooling reflect the use of the abdominal compression reaction to increase venous return during periods of diminished cardiac output.
Details
- Title: Subtitle
- Maintenance of arterial pressure in infant rats during moderate and extreme thermal challenge
- Creators
- R F Kirby - Department of Psychology, University of Iowa, Iowa City 52242, USAM S Blumberg
- Resource Type
- Journal article
- Publication Details
- Developmental psychobiology, Vol.32(3), pp.169-176
- DOI
- 10.1002/(SICI)1098-2302(199804)32:3<169::AID-DEV1>3.0.CO;2-M
- PMID
- 9553727
- NLM abbreviation
- Dev Psychobiol
- ISSN
- 0012-1630
- eISSN
- 1098-2302
- Publisher
- United States
- Grant note
- MH50701 / NIMH NIH HHS HL11390 / NHLBI NIH HHS
- Language
- English
- Date published
- 04/1998
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute; Biology
- Record Identifier
- 9984002577302771
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