Journal article
Male gender, smoking, younger age, and preoperative pain found to increase postoperative opioid requirements in 592 elective colorectal resections
International journal of colorectal disease, Vol.37(8), pp.1799-1806
08/01/2022
DOI: 10.1007/s00384-022-04208-5
PMID: 35796873
Abstract
Purpose With increased awareness of the opioid epidemic, understanding contributing factors to postoperative opioid use is important. The purpose of this study was to evaluate patient and perioperative factors that contribute to postoperative opioid use after colorectal resections and their relation to pre-existing pain conditions and psychiatric diagnoses. Methods A retrospective review was conducted identifying adult patients who underwent elective colorectal resection at a single tertiary center between 2015 and 2018. Patient demographics, preoperative factors, surgical approach, and perioperative pain management were evaluated to determine standard conversion morphine milligram equivalents required for postoperative days 0 to 3 and total hospital stay. Results Five hundred and ninety-two patients: 46% male, median age 58 years undergoing colorectal resections for indications including cancer, inflammatory bowel disease, and diverticulitis were identified. Less opioid use was found to be associated with female gender (beta = - 42), patients who received perioperative lidocaine infusion (beta = - 30), and older adults (equivalents/year) (beta = - 4, all p < 0.01). Preoperative opioid use, preoperative abdominal pain, epidural use, and smoking were all independently associated with increased postoperative opioid requirements. Conclusions In this study of patients undergoing elective colorectal resection, factors that were associated with higher perioperative opioid use included male gender, smoking, younger age, preoperative opioid use, preoperative abdominal pain, and epidural use. Perioperative administration of lidocaine was associated with decreased opioid requirements. Understanding risk factors and stratifying postoperative pain regimens may aid in improved pain control and decrease long-term dependency.
Details
- Title: Subtitle
- Male gender, smoking, younger age, and preoperative pain found to increase postoperative opioid requirements in 592 elective colorectal resections
- Creators
- Bergljot R Karlsdottir - Univ Iowa Hosp & Clin, Dept Surg, Iowa City, IA 52242 USAPeige P Zhou - Cleveland Clin Florida, Dept Surg, Weston, FL USAJoyce Wahba - UCLA Medical CenterSarah L Mott - Univ Iowa, Holden Comprehens Canc Ctr, Iowa City, IA 52242 USAPaolo Goffredo - University of MinnesotaJennifer Hrabe - University of Iowa Hospitals and ClinicsImran Hassan - University of Iowa Hospitals and ClinicsMuneera R Kapadia - Univ N Carolina, Dept Surg, Chapel Hill, NC 27515 USAIrena Gribovskaja-Rupp - Univ Iowa Hosp & Clin, Dept Surg, Iowa City, IA 52242 USA
- Resource Type
- Journal article
- Publication Details
- International journal of colorectal disease, Vol.37(8), pp.1799-1806
- Publisher
- Springer Nature
- DOI
- 10.1007/s00384-022-04208-5
- PMID
- 35796873
- ISSN
- 0179-1958
- eISSN
- 1432-1262
- Number of pages
- 8
- Language
- English
- Date published
- 08/01/2022
- Academic Unit
- Surgery
- Record Identifier
- 9984322959102771
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