Journal article
Malignant Tourette’s Syndrome in an Adult on Deep Brain Stimulation Presenting With Rhabdomyolysis
Curēus (Palo Alto, CA), Vol.15(8), e44436
08/31/2023
DOI: 10.7759/cureus.44436
PMCID: PMC10543999
PMID: 37791204
Abstract
Tourette's syndrome (TS) patients experiencing severe tics and behavioral disturbances can have a rare complication called rhabdomyolysis (RML), which is characterized by the breakdown of muscle tissue. The occurrence of RML poses a significant physical and emotional risk to patients with TS by impacting the quality of life and in some cases causing severe damage. In this case report, we present the first documented case of RML resulting from severe tics in an adult with a diagnosis of TS. The patient exhibited severe tics and self-injurious behaviors that led to elevated creatine kinase and a subsequent diagnosis of RML requiring hospitalization with a complex hospital course. The patient did not have neuroleptic malignant syndrome as his laboratory parameters improved with the decrease in severity of tics. Our case highlights the potential complication of RML because of severe tics independent of neuroleptic drug use in a patient with TS.
Details
- Title: Subtitle
- Malignant Tourette’s Syndrome in an Adult on Deep Brain Stimulation Presenting With Rhabdomyolysis
- Creators
- Varun MongaRohit MadanNiraj Arora
- Resource Type
- Journal article
- Publication Details
- Curēus (Palo Alto, CA), Vol.15(8), e44436
- DOI
- 10.7759/cureus.44436
- PMID
- 37791204
- PMCID
- PMC10543999
- NLM abbreviation
- Cureus
- ISSN
- 2168-8184
- eISSN
- 2168-8184
- Language
- English
- Date published
- 08/31/2023
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984463084102771
Metrics
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