Journal article
Malignant cervical schwannoma: An unusual pelvic tumor
Gynecologic oncology, Vol.72(2), pp.238-242
02/01/1999
DOI: 10.1006/gyno.1998.5234
Abstract
Background.Primary malignant cervical schwannomas (malignant peripheral nerve sheath tumors) are extremely rare tumors that grossly may resemble many other more common lesions. The diagnosis, management, and follow-up of a malignant cervical schwannoma are presented with a review of the literature.
Case.A 51-year-old female presented with a 3-year history of perimenopausal vaginal bleeding. A 3 × 3 cm friable, spongy lesion was noted on the posterior aspect of the cervix. Frozen-section analysis could not rule out a malignant smooth muscle tumor. The patient underwent an exploratory laparotomy, total abdominal hysterectomy, and bilateral salpingo-oophorectomy. Immunohistochemistry and electron microscopy aided in the final diagnosis of a malignant cervical schwannoma. The patient is alive and well 1 year from her definitive surgery. Another patient with the same tumor received the same surgical management. This patient is now 10 years from her surgery and is alive with no evidence of disease.
Conclusion.Immunohistochemistry and electron microscopy are useful in the diagnosis of a malignant cervical schwannoma. This case and long-term follow-up from another case provide evidence that simple hysterectomy may be sufficient therapy for this uncommon lesion.
Details
- Title: Subtitle
- Malignant cervical schwannoma: An unusual pelvic tumor
- Creators
- J. I. SoroskyBradley J. Van Voorhis - University of IowaT. A. LallasD. J. LagerP. C. Mehaffey
- Resource Type
- Journal article
- Publication Details
- Gynecologic oncology, Vol.72(2), pp.238-242
- DOI
- 10.1006/gyno.1998.5234
- ISSN
- 0090-8258
- Language
- English
- Date published
- 02/01/1999
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9983557423002771
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