Journal article
Mammographic Appearances in Mongolia: Causal Factors for Varying Densities
Asian Pacific journal of cancer prevention : APJCP, Vol.18(9), pp.2425-2430
09/27/2017
DOI: 10.22034/APJCP.2017.18.9.2425
PMCID: PMC5720646
PMID: 28952021
Abstract
Objective: Mammographic density (MD) is a significant risk factor for breast cancer and an important determinant
for establishing efficiency of any screening program. Currently, the distribution and influential factors of MD is unknown
among Mongolian women. This work aims to characterize MD of Mongolian women. Methods: The ethical approval
was obtained from Research Ethics Board of the University of Sydney (2014/973) and National Ethic Committee from
Ministry of Mongolia (2015/04). We recruited 1985 women aged 16-83 from the National Cancer Center in Mongolia
for whom MD and age of each woman was known. From this total group, 983 women also had additional available
details on height, weight, body mass index (BMI) and area of residency. We investigated the association of each of
these variables with breast density, which was assessed by using the Breast Imaging Reporting and Data System
(BIRADS) lexicon. Univariate and multivariate regression analyses were conducted to explore the importance of these
variables as predictors of MD. Results: Category B (33%) was the most common type of MD, whereas 25%, 18% and
24% of women belonged to the category A, C and D respectively. The univariate analysis demonstrated that, younger
women had more dens breasts than their older counterparts (OR=6.8). Also, increased MD was significantly (p<0.05)
associated with decreased weight (OR=4.5), increased height (OR=0.4) and lower BMI (OR=13.2). Urban women had
significantly higher MD compared with rural counterparts (OR=2.2). In the multivariate analysis, 75% of variation in
MD was explained by age (OR=4.5) and BMI (OR=7.3). Conclusion: A high proportion of Mongolian women have
very high density breasts and age and body size are key factors determining MD among these women.
Details
- Title: Subtitle
- Mammographic Appearances in Mongolia: Causal Factors for Varying Densities
- Creators
- Delgermaa Demchig - Medical Image Optimization and Perception Group (MIOPeG), Discipline of Medical Radiation Science, Faculty of Health Science, University of Sydney, Sydney, Australia. Email: Delgermaa.demchig@sydney.edu.auClaudia Mello-ThomsKhulan KhurelsukhAsai RamishPatrick C Brennan
- Resource Type
- Journal article
- Publication Details
- Asian Pacific journal of cancer prevention : APJCP, Vol.18(9), pp.2425-2430
- DOI
- 10.22034/APJCP.2017.18.9.2425
- PMID
- 28952021
- PMCID
- PMC5720646
- NLM abbreviation
- Asian Pac J Cancer Prev
- ISSN
- 1513-7368
- eISSN
- 2476-762X
- Publisher
- Thailand
- Language
- English
- Date published
- 09/27/2017
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology
- Record Identifier
- 9984051763202771
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