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Mammography adherence in relation to function-related indicators in older women
Journal article   Peer reviewed

Mammography adherence in relation to function-related indicators in older women

Dongyu Zhang, Linn Abraham, Brian L Sprague, Tracy Onega, Shailesh Advani, Joshua Demb, Diana L Miglioretti, Louise M Henderson, Karen J Wernli, Louise C Walter, …
Preventive medicine, Vol.154, pp.106869-106869
01/2022
DOI: 10.1016/j.ypmed.2021.106869
PMCID: PMC8724400
PMID: 34762965
url
https://escholarship.org/content/qt4tx2x57r/qt4tx2x57r.pdfView
Open Access

Abstract

Prior studies of screening mammography patterns by functional status in older women show inconsistent results. We used Breast Cancer Surveillance Consortium-Medicare linked data (1999–2014) to investigate the association of functional limitations with adherence to screening mammography in 145,478 women aged 66–74 years. Functional limitation was represented by a claims-based function-related indicator (FRI) score which incorporated 16 items reflecting functional status. Baseline adherence was defined as mammography utilization 9–30 months after the index screening mammography. Longitudinal adherence was examined among women adherent at baseline and defined as time from the index mammography to end of the first 30-month gap in mammography. Multivariable logistic regression and Cox proportional hazards models were used to investigate baseline and longitudinal adherence, respectively. Subgroup analyses were conducted by age (66–70 vs. 71–74 years). Overall, 69.6% of participants had no substantial functional limitation (FRI score 0), 23.5% had some substantial limitations (FRI score 1), and 6.8% had serious limitations (FRI score ≥ 2). Mean age at baseline was 68.5 years (SD = 2.6), 85.3% of participants were white, and 77.1% were adherent to screening mammography at baseline. Women with a higher FRI score were more likely to be non-adherent at baseline (FRI ≥ 2 vs. 0: aOR = 1.13, 95% CI = 1.06, 1.20, p-trend < 0.01). Similarly, a higher FRI score was associated with longitudinal non-adherence (FRI ≥ 2 vs. 0: aHR = 1.16, 95% CI = 1.11, 1.22, p-trend < 0.01). Effect measures of FRI did not differ substantially by age categories. Older women with a higher burden of functional limitations are less likely to be adherent to screening mammography recommendations. •Functional limitations are common in older women eligible for screening mammography.•Women with functional limitations are less likely to undergo screening mammography.•The association of functional limitations exists after adjusting for comorbidities.
Epidemiology Gerontology Breast cancer screening Functional limitation Mammography

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