Journal article
Management of functional neuroendocrine tumors
Current problems in cancer, Vol.52, p.101130
10/2024
DOI: 10.1016/j.currproblcancer.2024.101130
Abstract
Functional neuroendocrine neoplasms (NENs) are those associated with specific symptoms related to the hormonal secretion of the NENs. Although less than 25 % of NENs are functional at diagnosis,1 the associated syndromes significantly increase the patient burden of disease. Management of hormonal NEN symptoms may involve tumor resection or other reduction strategies (e.g., chemotherapy, embolotherapy, etc), but also specific therapies directed at decreasing hormonal synthesis, secretion, or end-organ effects. In this review, we focus on specific symptomatic management of many of the NEN syndromes, which may be pursued in addition to management primarily directed at tumor bulk and growth. A continued focus on symptom management related to the hormonal secretions of NENs, in the context of other efforts to reduce tumor bulk and growth, could significantly improve patient wellbeing.
Details
- Title: Subtitle
- Management of functional neuroendocrine tumors
- Creators
- Amr Wahba - University of IowaZi Tan - University of IowaJoseph S. Dillon - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Current problems in cancer, Vol.52, p.101130
- Publisher
- Elsevier Inc; NEW YORK
- DOI
- 10.1016/j.currproblcancer.2024.101130
- ISSN
- 0147-0272
- eISSN
- 1535-6345
- Language
- English
- Date published
- 10/2024
- Academic Unit
- Internal Medicine; Fraternal Order of Eagles Diabetes Research Center; Endocrinology and Metabolism
- Record Identifier
- 9984702944802771
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