Journal article
Management of sympathetic ophthalmia with the fluocinolone acetonide implant
Ophthalmology (Rochester, Minn.), Vol.116(3), pp.552-557.e1
03/2009
DOI: 10.1016/j.ophtha.2008.10.024
PMID: 19147232
Abstract
We examined whether implantation of the fluocinolone acetonide (Retisert) implant achieved control of inflammation and a reduced need for oral corticosteroids or immunosuppressives in patients with sympathetic ophthalmia (SO). Retrospective, noncomparative case series. Eight patients with active SO. The results of fluocinolone acetonide implantation in 8 patients with active SO were studied with a follow-up period of 6 months to 2 years. Presence or absence of intraocular inflammation, visual acuity, intraocular pressure, need for further surgery, and the need for additional use of oral or locally injected corticosteroids and/or immunosuppressives. All patients demonstrated a significant reduction in the systemic medication required to maintain control of inflammation. Two patients had recurrent inflammatory episodes requiring the resumption of an oral immunosuppressive. Vision improved or was stabilized in all 8 patients. The fluocinolone acetonide implant provides inflammatory control and reduces the dependence on systemic immunosuppression in patients with SO.
Details
- Title: Subtitle
- Management of sympathetic ophthalmia with the fluocinolone acetonide implant
- Creators
- Vinit B Mahajan - Department of Ophthalmology and Visual Sciences, The University of Iowa Hospitals & Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USAKaren M GehrsDebra A GoldsteinDavid H FischerJuan S Lopez - University of the Philippines ManilaJames C Folk
- Resource Type
- Journal article
- Publication Details
- Ophthalmology (Rochester, Minn.), Vol.116(3), pp.552-557.e1
- Publisher
- United States
- DOI
- 10.1016/j.ophtha.2008.10.024
- PMID
- 19147232
- ISSN
- 0161-6420
- eISSN
- 1549-4713
- Language
- English
- Date published
- 03/2009
- Academic Unit
- Stead Family Department of Pediatrics; Ophthalmology and Visual Sciences
- Record Identifier
- 9983979951602771
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