Journal article
Managing cholesterol in the elderly
Aging health, Vol.2(4), pp.623-638
08/2006
DOI: 10.2217/1745509X.2.4.623
Abstract
Statins have been shown conclusively to reduce the risk of cardiovascular events in patients aged 65–80 years with clinical cardiovascular disease. Less evidence is available for elderly patients with diabetes but without cardiovascular disease and for primary prevention with advancing age. Treatment guidelines recommend a low-density lipoprotein cholesterol goal of less than 100 mg/dl for those with cardiovascular disease or diabetes, but vary in their recommendations for primary prevention. Moderate-dose statins have been shown to be safe and effective in properly selected elderly patients. High-dose statins have also been demonstrated to be effective and reasonably safe in patients without significant comorbidities up to the age of 75. With advancing age, the potential for benefit from cholesterol treatment must be weighed against the increasing risk of muscle and hepatic toxicity.
Details
- Title: Subtitle
- Managing cholesterol in the elderly
- Creators
- Jennifer G Robinson - University of IowaMichael H Davidson - Rush University Medical Center
- Resource Type
- Journal article
- Publication Details
- Aging health, Vol.2(4), pp.623-638
- DOI
- 10.2217/1745509X.2.4.623
- ISSN
- 1745-509X
- eISSN
- 1745-5103
- Language
- English
- Date published
- 08/2006
- Academic Unit
- Epidemiology; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984363602602771
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