Mandible reconstruction with vascularized bone grafts. A histologic evaluation

H T Hoffman; Nancy Harrison; M J Sullivan; K T Robbins; M Ridley; Shan R Baker

doi:10.1001/archotol.1991.01870200111020

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Mandible reconstruction with vascularized bone grafts. A histologic evaluation

Journal article

Peer reviewed

Mandible reconstruction with vascularized bone grafts. A histologic evaluation

H T Hoffman, Nancy Harrison, M J Sullivan, K T Robbins, M Ridley and Shan R Baker

Archives of otolaryngology--head & neck surgery, Vol.117(8), pp.917-925

08/1991

DOI: 10.1001/archotol.1991.01870200111020

PMID: 1892626

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Abstract

To our knowledge, a histologic evaluation of bone healing after mandible reconstruction with vascularized human bone grafts has not been previously reported. Serial sections through both the decalcified graft and the junction between mandible and graft were evaluated in four patients who required surgical removal of their reconstructed mandibles. A failed scapular bone graft that had been wrapped within a pectoralis major myocutaneous flap for salvage following pedicle thrombosis showed markedly resorbed but viable bone with a fibrous union to the native mandible. Viable vascularized grafts without evidence of ongoing resorption characterized an iliac osteocutaneous bone graft and two scapula osteocutaneous grafts that healed with continuity of healthy bone between graft and mandible. Observations from the evaluation of these specimens are made regarding bone circulation, bone union, and bone graft survival as they occur clinically. Implications regarding the techniques of bone plating and indications for use of vascularized bone in mandible reconstruction are discussed.

Humans

Mandible - pathology

Middle Aged

Bone Transplantation

Carcinoma, Squamous Cell - surgery

Female

Graft Survival

Male

Mandibular Neoplasms - surgery

Neoplasm Recurrence, Local - surgery

Details

Title: Subtitle: Mandible reconstruction with vascularized bone grafts. A histologic evaluation
Creators: H T Hoffman - Department of Surgery, University of California, San Diego, Medical Center
Nancy Harrison
M J Sullivan
K T Robbins
M Ridley
Shan R Baker
Resource Type: Journal article
Publication Details: Archives of otolaryngology--head & neck surgery, Vol.117(8), pp.917-925
DOI: 10.1001/archotol.1991.01870200111020
PMID: 1892626
NLM abbreviation: Arch Otolaryngol Head Neck Surg
ISSN: 0886-4470
eISSN: 1538-361X
Publisher: American Medical Association; United States
Language: English
Date published: 08/1991
Academic Unit: Radiation Oncology; Otolaryngology
Record Identifier: 9984006458702771

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