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Mapping Pitch Representation in Neural Ensembles with fMRI
Journal article   Open access   Peer reviewed

Mapping Pitch Representation in Neural Ensembles with fMRI

Timothy D. Griffiths and Deborah A. Hall
The Journal of neuroscience, Vol.32(39), pp.13343-13347
09/26/2012
DOI: 10.1523/JNEUROSCI.3813-12.2012
PMCID: PMC6621372
PMID: 23015424
url
https://doi.org/10.1523/JNEUROSCI.3813-12.2012View
Published (Version of record) Open Access

Abstract

Functional magnetic resonance imaging (fMRI) in humans and macaques allows a test of the hypothesis that there is a specialized neural ensemble for pitch within auditory cortex: a pitch center. fMRI measures the blood oxygenation level-dependent (BOLD) response related to regional synaptic activity (Logothetis et al., 2001). The distinction between synaptic activity and spike firing, and species differences encourage caution when comparing BOLD activity in humans and macaques to recordings from single neurons in ferret and marmoset in the previous mini-review. The BOLD data provide support for the pitch-center concept, with ongoing debate about its location.
Life Sciences & Biomedicine Neurosciences Neurosciences & Neurology Science & Technology

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