Journal article
Mapping routine measles vaccination in low- and middle-income countries
Nature (London), Vol.589(7842), pp.415-419
01/21/2021
DOI: 10.1038/s41586-020-03043-4
PMCID: PMC7739806
PMID: 33328634
Abstract
The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)(1-4). Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)(5-8). Here we generated annual estimates of routine childhood MCV1 coverage at 5 x 5-km(2) pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children.
Details
- Title: Subtitle
- Mapping routine measles vaccination in low- and middle-income countries
- Creators
- Alyssa N. Sbarra - Institute for Health Metrics and EvaluationSam Rolfe - Institute for Health Metrics and EvaluationJason Q. Nguyen - Institute for Health Metrics and EvaluationLucas Earl - University of WashingtonNatalie C. Galles - Institute for Health Metrics and EvaluationAshley Marks - Institute for Health Metrics and EvaluationKaja M. Abbas - London School of Hygiene & Tropical MedicineMohsen Abbasi-Kangevari - Shahid Beheshti University of Medical SciencesHedayat Abbastabar - Tehran University of Medical SciencesFoad Abd-Allah - Cairo UniversityAhmed Abdelalim - Cairo UniversityMohammad Abdollahi - Tehran University of Medical SciencesKedir Hussein Abegaz - Near East UniversityHailemariam Abiy Alemu Abiy - Debre Markos UniversityHassan Abolhassani - Karolinska University HospitalLucas Guimaraes Abreu - Universidade Federal de Minas GeraisMichael R. M. Abrigo - Philippine Inst Dev Studies, Quezon City, PhilippinesAbdelrahman I. Abushouk - Cleveland ClinicManfred Mario Kokou Accrombessi - London Sch Hyg & Trop Med, Dept Dis Control, London, EnglandMaryam Adabi - Hamedan University of Medical SciencesOladimeji M. Adebayo - University College Hospital, IbadanVictor Adekanmbi - King's College LondonOlatunji O. Adetokunboh - Stellenbosch UniversityDavoud Adham - Ardabil University of Medical SciencesMohsen Afarideh - Mayo Clinic in ArizonaMohammad Aghaali - Qom University of Medical Science and Health ServicesTauseef Ahmad - Southeast UniversityRaman Ahmadi - Tabriz University of Medical SciencesKeivan Ahmadi - University of LincolnMuktar Beshir Ahmed - Jimma UniversityFahad Mashhour Alanezi - Imam Abdulrahman Bin Faisal UniversityTurki M. Alanzi - Imam Abdulrahman Bin Faisal UniversityJacqueline Elizabeth Alcalde-Rabanal - Instituto Nacional de Salud PúblicaBirhan Tamene Alemnew - Woldia UniversityBeriwan Abdulqadir Ali - Sulaimani Polytechnic UniversityMuhammad Ali - Quaid-i-Azam UniversityMehran Alijanzadeh - Qazvin University of Medical SciencesCyrus Alinia - Urmia UniversityReza Alipoor - Hormozgan University of Medical SciencesVahid Alipour - Iran University of Medical SciencesHesam Alizade - Hormozgan University of Medical SciencesSyed Mohamed Aljunid - Kuwait UniversityAli Almasi - Kermanshah University of Medical SciencesAmir Almasi-Hashiani - Arak University of Medical SciencesHesham M. Al-Mekhlafi - Jazan UniversityKhalid A. Altirkawi - King Saud UniversityBekalu Amare - Mekelle UniversitySaeed Amini - Arak UniversityMostafa Amini-Rarani - Isfahan University of Medical SciencesFatemeh Amiri - Kermanshah University of Medical SciencesArianna Maever L. Amit - Johns Hopkins UniversityDickson A. Amugsi - African Population and Health Research CenterRobert Ancuceanu - Carol Davila University of Medicine and PharmacyCatalina Liliana Andrei - Carol Davila University of Medicine and PharmacyMina Anjomshoa - Rafsanjan University of Medical SciencesFereshteh Ansari - Tabriz University of Medical SciencesAlireza Ansari-Moghaddam - Zahedan University of Medical SciencesMustafa Geleto Ansha - Debre Berhan UniversityCarl Abelardo T. Antonio - University of the Philippines ManilaErnoiz Antriyandarti - Sebelas Maret UniversityDavood Anvari - Mazandaran University of Medical SciencesJalal Arabloo - Iran University of Medical SciencesMorteza Arab-Zozani - Birjand University of Medical SciencesOlatunde Aremu - Birmingham City UniversityBahram Armoon - Saveh University of Medical SciencesKrishna K. Aryal - Schulman, Ronca & BucuvalasAfsaneh Arzani - Babol University of Medical SciencesMehran Asadi-Aliabadi - Iran University of Medical SciencesSamaneh Asgari - Shahid Beheshti University of Medical SciencesZahra Atafar - Kermanshah University of Medical SciencesMarcel Ausloos - University of LeicesterNefsu Awoke - Wolaita Sodo UniversityBeatriz Paulina Ayala Quintanilla - La Trobe UniversityMartin Amogre Ayanore - University of Health and Allied SciencesYared Asmare Aynalem - Debre Berhan UniversityAbbas Azadmehr - Babol University of Medical SciencesSamad Azari - Iran University of Medical SciencesEbrahim Babaee - Iran University of Medical SciencesAlaa Badawi - Public Health Agency of CanadaAshish D. Badiye - Central Forensic Science LaboratoryMohammad Amin Bahrami - Shiraz University of Medical SciencesAtif Amin Baig - Sultan Zainal Abidin UniversityAhad Bakhtiari - Tehran University of Medical SciencesSenthilkumar Balakrishnan - Haramaya UniversityMaciej Banach - Medical University of LodzPalash Chandra Banik - Bangladesh University of Health SciencesAleksandra Barac - Clin Ctr Serbia, Clin Infect & Trop Dis, Belgrade, SerbiaZahra Baradaran-Seyed - Razi Vaccine and Serum Research InstituteAdhanom Gebreegziabher Baraki - University of GondarSanjay Basu - Harvard UniversityMohsen Bayati - Shiraz University of Medical SciencesYibeltal Tebekaw Bayou - JSI Res & Training Inst, Monitoring Evaluat & Res Dept, Addis Ababa, EthiopiaNeeraj Bedi - Jazan UniversityMasoud Behzadifar - Lorestan University of Medical SciencesMichelle L. Bell - Yale UniversityDessalegn Ajema Berbada - Arba Minch UniversityKidanemaryam Berhe - Mekelle UniversitySuraj Bhattarai - Global Inst Interdisciplinary Studies, Dept Global Hlth, Kathmandu, NepalZulfiqar A. Bhutta - Centre for Global Health ResearchAli Bijani - Babol University of Medical SciencesLocal Burden of Disease Vaccine Coverage CollaboratorsDavid C Schwebel (Contributor) - Research Administration
- Resource Type
- Journal article
- Publication Details
- Nature (London), Vol.589(7842), pp.415-419
- DOI
- 10.1038/s41586-020-03043-4
- PMID
- 33328634
- PMCID
- PMC7739806
- NLM abbreviation
- Nature
- ISSN
- 0028-0836
- eISSN
- 1476-4687
- Publisher
- NATURE PORTFOLIO
- Number of pages
- 27
- Grant note
- XMUMRF/2018-C2/ITCM/0001 / Research Management Centre, Xiamen University Malaysia NIGEB P_40_382 / European Fund for Regional Development through Operational Program for Competitiveness Alexander von Humboldt Foundation OPP1182474; OPP11093011; OPP1132415; OPP1119467; OPP1106023 / Bill AMP; Melinda Gates Foundation; CGIAR DST PURSE Grant UGC Centre of Advanced Study BHF Centre of Research Excellence, Oxford NIMAD OPP1182474 / Bill and Melinda Gates Foundation; Bill & Melinda Gates Foundation
- Language
- English
- Date published
- 01/21/2021
- Academic Unit
- Research Administration
- Record Identifier
- 9984949188502771
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