Journal article
Marfan syndrome and schizophrenia: a case report and literature review
General hospital psychiatry, Vol.32(2), pp.228.e9-228.e10
03/2010
DOI: 10.1016/j.genhosppsych.2009.04.010
PMCID: PMC3253300
PMID: 20303004
Abstract
Marfan Syndrome (MFS), a disease of microfibril dysfunction, has been associated with schizophrenia in multiple case reports.
We present one case and review the literature that suggests these conditions may share a common etiologic pathway.
A possible underlying mechanism of both schizophrenia and MFS is the abnormal expression of growth factors and signaling cascades.
MFS patients should be monitored for psychiatric symptoms and patients with signs of MFS should be referred for appropriate medical care. Also, by understanding shared mechanisms, we may develop better understanding and treatments.
Details
- Title: Subtitle
- Marfan syndrome and schizophrenia: a case report and literature review
- Creators
- Mary Lemberg - University of Washington Medical Center, Box 356560, Seattle, WA 98195-6560, USAAlexander W Thompson
- Resource Type
- Journal article
- Publication Details
- General hospital psychiatry, Vol.32(2), pp.228.e9-228.e10
- DOI
- 10.1016/j.genhosppsych.2009.04.010
- PMID
- 20303004
- PMCID
- PMC3253300
- NLM abbreviation
- Gen Hosp Psychiatry
- ISSN
- 0163-8343
- eISSN
- 1873-7714
- Publisher
- United States
- Grant note
- T32 MH020021 / NIMH NIH HHS T32 MH020021-09 / NIMH NIH HHS
- Language
- English
- Date published
- 03/2010
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003468902771
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