Logo image
Mass of left ventricular myocardium estimated with dynamic spatial reconstructor
Journal article   Peer reviewed

Mass of left ventricular myocardium estimated with dynamic spatial reconstructor

Tsutomu Iwasaki, Lawrence J Sinak, Eric A Hoffman, Richard A Robb, Lowell D Harris, Robert C Bahn and Erik L Ritman
The American journal of physiology, Vol.246(1 Pt 2), pp.H138-H142
01/01/1984
DOI: 10.1152/ajpheart.1984.246.1.h138
PMID: 6696086

View Online

Abstract

Using the Dynamic Spatial Reconstructor (DSR), a unique multiple X-ray source, high-repetition-rate CAT scanner, we estimated left ventricular (LV) myocardial volume and chamber volume of eight dogs ranging from 2.5 to 32.5 kg. Dogs were given subcutaneous morphine (3 mg/kg) and anesthetized with intravenous pentobarbital sodium (22 mg/kg). A bolus of 1 ml/kg body wt contrast medium was injected into the superior vena cava and 60/s scans repeated over 7 s were performed. Each 0.0167-s scan generated image data for 120 1.8-mm-thick transverse slices, in the dextro and levo phases of the angiograms. Retrospective reformatting of the scan data was used to generate images of thin slices perpendicular to the aortoapical axis of the LV. The LV muscle and chamber volumes were estimated from their outlines in each imaged slice using a manually operated trackball interfaced to a computer. Values of the LV muscle ranged from 18.0 to 146.8 cm3 by DSR and showed a good correlation with the postmortem values (r = 0.99, y = 0.94x + 4.1). Ratios of volume of the myocardium to chamber volume ranged from 1.19 to 3.10.

Details

Logo image