Maternal reporting of prenatal ultrasounds among women in the National Birth Defects Prevention Study

Ashley E Weedn; Bridget S Mosley; Mario A Cleves; D. Kim Waller; Mark A Canfield; Adolfo Correa; Charlotte A Hobbs; National Birth Defects Prevention Study

doi:10.1002/bdra.23178

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Maternal reporting of prenatal ultrasounds among women in the National Birth Defects Prevention Study

Journal article

Open access

Peer reviewed

Maternal reporting of prenatal ultrasounds among women in the National Birth Defects Prevention Study

Ashley E Weedn, Bridget S Mosley, Mario A Cleves, D. Kim Waller, Mark A Canfield, Adolfo Correa, Charlotte A Hobbs and National Birth Defects Prevention Study

Birth defects research. A Clinical and molecular teratology, Vol.100(1), pp.4-12

01/2014

DOI: 10.1002/bdra.23178

PMID: 24123727

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Abstract

Background Increased availability and usage of ultrasound screening have led to improved identification of fetal structural abnormalities prenatally. Few population‐based studies have been published on prenatal detection for structural birth defects in the United States. The aim of this study is to determine the frequency of maternal reporting of abnormal prenatal ultrasounds for selected birth defects and to investigate associated maternal characteristics. Methods Participants included 4013 mothers enrolled in the National Birth Defects Prevention Study who carried a fetus with at least one of 14 structural birth defects between 1997 and 2004. Frequencies of abnormal prenatal ultrasounds were based on maternal report and computed for isolated and multiple defects. Associations between maternal characteristics and abnormal prenatal ultrasounds were assessed using logistic regression. Results Overall, 46% of participants reported an abnormal ultrasound. Infants with omphalocele, anencephaly, gastroschisis, and renal agenesis were more likely to have abnormal prenatal ultrasounds than those with cleft and limb abnormalities. Hispanic women were less likely to report abnormal prenatal ultrasounds of birth defects than Caucasians, as were women who had a body mass index ≥ 30 kg/m2 compared with those with a normal body mass index. CONCLUSION Of the 14 selected birth defects in this study, less than half were reported by mothers of affected infants to have had an abnormal ultrasound during pregnancy. The frequency of reporting abnormal prenatal ultrasounds varies by type of defect, maternal race/ethnicity, and maternal body mass index status. Birth Defects Research (Part A) 100:4–12, 2014. © 2013 Wiley Periodicals, Inc.

birth defects, maternal report

National Birth Defects Prevention Study

prenatal diagnosis

prenatal ultrasound

Details

Title: Subtitle: Maternal reporting of prenatal ultrasounds among women in the National Birth Defects Prevention Study
Creators: Ashley E Weedn - University of Oklahoma Health Sciences Center
Bridget S Mosley - Arkansas Children's Hospital Research Institute
Mario A Cleves - Arkansas Children's Hospital Research Institute
D. Kim Waller - University of Texas Health Sciences Center
Mark A Canfield - Texas Department of State Health Services
Adolfo Correa - University of Mississippi Medical Center
Charlotte A Hobbs - Arkansas Children's Hospital Research Institute
National Birth Defects Prevention Study
Contributors: Paul A Romitti (Contributor) - University of Iowa, Epidemiology
Resource Type: Journal article
Publication Details: Birth defects research. A Clinical and molecular teratology, Vol.100(1), pp.4-12
DOI: 10.1002/bdra.23178
PMID: 24123727
NLM abbreviation: Birth Defects Res A Clin Mol Teratol
ISSN: 1542-0752
eISSN: 1542-0760
Publisher: Wiley
Number of pages: 7
Grant note: Centers for Disease Control and Prevention (5U01DD000491‐02)
Language: English
Date published: 01/2014
Academic Unit: Epidemiology; Biostatistics
Record Identifier: 9984214696002771

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