Journal article
Maximizing opportunities for kidney transplantation in older adults
Current opinion in nephrology and hypertension, Vol.32(2), pp.204-211
03/2023
DOI: 10.1097/MNH.0000000000000871
PMID: 36633323
Abstract
To summarize the current state of evidence related to the outcomes of older adults who need and receive kidney transplants, and strategies to facilitate appropriate transplant access in this at-risk group.
Older adults (65+) are a rapidly growing subgroup of the kidney transplant waitlist. Compared to younger adults, older kidney transplant recipients have increased mortality after kidney transplant and lower death-censored graft survival. In determining suitability for transplantation in older patients, clinicians must balance procedural and immunosuppression-related risk with incremental survival when compared with dialysis. To appropriately increase access to transplantation in this population, clinicians and policy makers consider candidates' chronological age and frailty, as well as the quality of and waiting time for a donated allograft. Given risk of deterioration prior to transplant, candidates should be rapidly evaluated, listed, and transplanted using living donor and or less than ideal deceased donors when available.
Access to transplantation for older adults can be increased through targeted interventions to address frailty and reduce waiting times. Focused study and educational interventions for patients and providers are needed to improve the outcomes of this vulnerable group.
Details
- Title: Subtitle
- Maximizing opportunities for kidney transplantation in older adults
- Creators
- Vidya A Fleetwood - Saint Louis University HospitalYasar Caliskan - Saint Louis University HospitalFadee Abu Al Rub - Saint Louis University HospitalDavid Axelrod - University of IowaKrista L Lentine - Saint Louis University Hospital
- Resource Type
- Journal article
- Publication Details
- Current opinion in nephrology and hypertension, Vol.32(2), pp.204-211
- DOI
- 10.1097/MNH.0000000000000871
- PMID
- 36633323
- ISSN
- 1062-4821
- eISSN
- 1473-6543
- Language
- English
- Electronic publication date
- 01/12/2023
- Date published
- 03/2023
- Academic Unit
- Surgery
- Record Identifier
- 9984359613902771
Metrics
5 Record Views