Journal article
Measurement and comparison of T1 relaxation times in native and transplanted kidney cortex and medulla
Journal of magnetic resonance imaging, Vol.33(5), pp.1241-1247
05/2011
DOI: 10.1002/jmri.22543
PMCID: PMC3081137
PMID: 21509885
Abstract
To measure and compare cortical and medullary T1 values in native and transplanted kidneys with a wide range of function as measured by estimated glomerular filtration rate (eGFR).
A total of 27 subjects (12 native and 15 transplants) were studied. Two magnetic resonance imaging (MRI) exams of T1 measurement were performed on separate days for reproducibility study. Group-wise comparisons of renal T1 on day 1 were performed between subjects with native and transplanted kidneys and also between subjects based on an eGFR threshold of 60 mL/min/1.73 m(2).
Transplanted kidneys had higher cortical renal T1 (1183 ± 136 msec) than native kidneys (1057 ± 94 msec) with similar results in the medulla. Subjects with an eGFR < 60 mL/min/1.73 m(2) had higher renal T1 than subjects with an eGFR > 60 mL/min/1.73 m(2) (cortical T1: P < 0.0001; medullary T1: P = 0.008). Renal T1 was highly reproducible for both native and transplant groups (with percent differences less than 10%).
There are differences in cortical and medullary T1 between native and transplanted kidneys at different levels of function.
Details
- Title: Subtitle
- Measurement and comparison of T1 relaxation times in native and transplanted kidney cortex and medulla
- Creators
- Yin Huang - University of Wisconsin–MadisonElizabeth A Sadowski - University of Wisconsin–MadisonNathan S Artz - University of Wisconsin–MadisonSongwon Seo - University of Wisconsin–MadisonArjang Djamali - University of Wisconsin–MadisonThomas M Grist - University of Wisconsin–MadisonSean B Fain - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- Journal of magnetic resonance imaging, Vol.33(5), pp.1241-1247
- DOI
- 10.1002/jmri.22543
- PMID
- 21509885
- PMCID
- PMC3081137
- ISSN
- 1053-1807
- eISSN
- 1522-2586
- Grant note
- R01 DK073680 / NIDDK NIH HHS R21 DK070243-01A1 / NIDDK NIH HHS R21 DK070243 / NIDDK NIH HHS R01 DK 073680 / NIDDK NIH HHS R01 DK073680-01 / NIDDK NIH HHS R21 DK 070243 / NIDDK NIH HHS
- Language
- English
- Date published
- 05/2011
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Health and Human Physiology
- Record Identifier
- 9984275053002771
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