Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults

Patricia H Davis; Jeffrey D Dawson; M. Beth Blecha; Rebecca K Mastbergen; Milan Sonka

doi:10.1016/j.ultrasmedbio.2010.01.002

Back

Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults

Journal article

Open access

Peer reviewed

Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults

Patricia H Davis, Jeffrey D Dawson, M. Beth Blecha, Rebecca K Mastbergen and Milan Sonka

Ultrasound in medicine & biology, Vol.36(4), pp.560-565

2010

DOI: 10.1016/j.ultrasmedbio.2010.01.002

PMCID: PMC2851193

PMID: 20350682

Files and links (1)

url

https://doi.org/10.1016/j.ultrasmedbio.2010.01.002View

Published (Version of record) Open Access

Abstract

Atherosclerosis begins in childhood in the distal abdominal aorta and later involves the carotid arteries. Noninvasive screening to detect these lesions may allow early intervention. Ultrasound images of the distal 10 mm of the aorta were obtained after an 8-h fast and were analyzed by an automated program to determine the mean far wall intimal-medial thickness (IMT). The results were compared with the mean carotid IMT obtained concurrently. The mean age of the 313 males and 322 females imaged was 20.4 years (SD 5.6) and 61 participants had a second study to assess reproducibility. The mean aortic IMT was 0.63 mm (SD 0.14) for males and 0.61 mm (SD 0.13) for females while the mean carotid IMT was 0.50 (SD 0.04) mm and 0.49 (SD 0.04) mm, respectively. Images were analyzed in 95% of participants. Intra-subject reproducibility for the mean aortic IMT had a coefficient of variation of 18% with a mean absolute difference of 0.12 mm (SD 0.10). For carotid IMT, the results were 3% and 0.02 mm (SD 0.01), respectively. Aortic IMT can be measured in normal adolescents and young adults with low rates of missing data and reasonable reproducibility. Aortic IMT increased with age at a greater rate than carotid IMT. (E-mail: pat-davis@uiowa.edu)

Aorta

Ultrasound

Carotid arteries

Atherosclerosis

Details

Title: Subtitle: Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults
Creators: Patricia H Davis - Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA
Jeffrey D Dawson - Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USA
M. Beth Blecha - Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA
Rebecca K Mastbergen - Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USA
Milan Sonka - Department of Electrical and Computer Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA
Resource Type: Journal article
Publication Details: Ultrasound in medicine & biology, Vol.36(4), pp.560-565
DOI: 10.1016/j.ultrasmedbio.2010.01.002
PMID: 20350682
PMCID: PMC2851193
NLM abbreviation: Ultrasound Med Biol
ISSN: 0301-5629
eISSN: 1879-291X
Publisher: Elsevier Inc
Grant note: DOI: 10.13039/100000002, name: National Institutes of Health, award: HL54730
Language: English
Date published: 2010
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Neurology; Public Health Administration; Electrical and Computer Engineering; Biostatistics; Radiation Oncology; Injury Prevention Research Center; Ophthalmology and Visual Sciences
Record Identifier: 9983997303102771

Metrics

26 Record Views

41 Times Cited - Web of Science