Journal article
Mechanical behavior of carpal tunnel subsynovial connective tissue under compression
The Iowa orthopaedic journal, Vol.31, pp.127-132
2011
PMCID: PMC3215125
PMID: 22096431
Appears in Diamond Open Access
Abstract
Subsynovial connective tissue (SSCT) is a fluid-permeated loose connective tissue that occupies the majority of the space in the carpal tunnel not occupied by the digital flexor tendons or the median nerve. It is arranged in layers around these more discrete structures, presumably to assist with tendon gliding. As a result of this arrangement, the compressive behavior and the fluid permeability of this tissue may substantially affect the stresses in the median nerve resulting from contact with its neighboring tendons or with the walls of the tunnel itself. These stresses may contribute to damage of the median nerve and the development of carpal tunnel syndrome. In this study, the fluid permeability and the compressive behavior of the SSCT were investigated to better understand the mechanics of this tissue and how it may mediate mechanical insult to the median nerve. A custom experimental apparatus was built to allow simultaneous measurement of tissue compression and fluid flow. Using Darcy's law, the average SSCT fluid permeability was 8.78×10(15) m(4)/Ns. The compressive behavior of the SSCT demonstrated time dependence, with an initial modulus of 395kPa gradually decreasing to a value of 285kPa. These baseline tissue data may serve as a mechanical norm (toward which pathological tissue might be returned, therapeutically) and may serve as essential properties to include in future mechanical models of the carpal tunnel.
Details
- Title: Subtitle
- Mechanical behavior of carpal tunnel subsynovial connective tissue under compression
- Creators
- Jessica E Goetz - Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, USA. jessica-goetz@uiowa.eduThomas E Baer
- Resource Type
- Journal article
- Publication Details
- The Iowa orthopaedic journal, Vol.31, pp.127-132
- Publisher
- Dept. of Orthopaedics, The University of Iowa; United States
- PMID
- 22096431
- PMCID
- PMC3215125
- ISSN
- 1541-5457
- eISSN
- 1555-1377
- Language
- English
- Date published
- 2011
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation
- Record Identifier
- 9984040204302771
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